赛洛多辛(Silodosin)怎么购买

Silodosin is a highly selective α1A-adrenergic receptor antagonist that can improve urinary function.

How to buy Silodosin

It is a prescription drug and cannot be purchased directly in pharmacies. It must be obtained with a doctor's prescription.

Patients need to go to the urology department or related departments of the hospital first. After the doctor makes a diagnosis that meets the medication indications and issues a prescription, they can then pick up the medicine at the hospital's internal pharmacy. Patients with a doctor's prescription can also purchase from large chain pharmacies or brick-and-mortar pharmacies that are qualified to sell prescription drugs. The pharmacist will verify the prescription information before dispensing the medicine.

Tip: Drug prices vary depending on specifications (4mg/8mg), brands, regions and medical insurance policies. It is recommended to consult local medical institutions or pharmacies to obtain accurate prices.

The pictures are from public channels (such as the official website of the FDA, the official website of the original drug manufacturer, etc.) and are for reference only.

Precautions for purchasing and using Silodosin

1. Strictly follow the prescription

It must be purchased with a prescription from a licensed physician, and you are not allowed to self-administer or adjust the dosage. The recommended dose is 8 mg once daily, taken with food to reduce potential side effects.

2. Identify medication contraindications

(1) It is contraindicated in patients with severe renal insufficiency (creatinine clearance CCr<30mL/min).

(2) It is contraindicated in patients with severe hepatic insufficiency (Child-Pugh score ≥ 10).

(3) It is forbidden for those allergic to silodosin or any ingredients.

(4) It is prohibited to use it simultaneously with strong CYP3A4 inhibitors (such as ketoconazole, clarithromycin, itraconazole, ritonavir), otherwise it may lead to a significant increase in blood concentration and increase the risk of side effects.

3. Be wary of drug interactions

(1) It should not be combined with other α-blockers (such as tamsulosin, doxazosin).

(2). Combination with PDE5 inhibitors (such as sildenafil, tadalafil) may increase the risk of hypotension, so caution is required.

(3) When used in combination with antihypertensive drugs, blood pressure needs to be monitored closely to prevent orthostatic hypotension.

(4) Obligation to inform before surgery: Patients who plan to undergo cataract surgery must inform their ophthalmologists in advance that they are using or have used silodosin to prevent the occurrence of "intraoperative floppy iris syndrome" (IFIS).

(5) Be wary of dizziness during the initial medication period: Dizziness or orthostatic hypotension may occur in the early stages of medication. Driving, operating machinery, or working at high altitudes and other dangerous activities should be avoided until the physical reaction is clear.

Silodosin (Silodosin) Medication for Special Populations

1. Elderly Patients

Growing age does not affect the recommended dose, but the risk of orthostatic hypotension increases with age, especially for patients over 75 years old, who need to strengthen monitoring when starting medication.

2. Patients with renal insufficiency

(1), moderate renal insufficiency (CCr30-50mL/min): The dose should be reduced to 4 mg once a day.

(2) Severe renal insufficiency (CCr<30mL/min): use is prohibited.

3. Patients with hepatic insufficiency

(1) Mild to moderate hepatic insufficiency: No dose adjustment is required.

(2) Severe liver insufficiency: use is prohibited.

4. Children and Adolescents

This product is not suitable for people under the age of 18, and its safety and effectiveness have not been established.

5. Men of childbearing age

Animal experiments show that high doses may have a reversible effect on fertility, but the clinical relevance is unknown. Patients with fertility needs can consult a doctor before taking the drug.