赛洛多辛(Silodosin)临床中用于治疗什么疾病

Silodosin was first approved for marketing in Japan in 2008 and has been licensed for use in many countries and regions around the world. It is also now available in China. Patients can also rely on medical insurance to reimburse the purchase cost of silodosin.

What diseases is Silodosin used to treat clinically?

Benign prostatic hyperplasia (BPH)

Silodosin has a good antispasmodic and relaxing effect on the smooth muscles of the prostate and bladder neck through its selective antagonism to α1A-adrenaline, thereby improving the circulation of urine and alleviating the patient's difficulty in urinating.

Improvement of lower urinary tract symptoms

Silodosin can effectively alleviate various lower urinary tract symptoms of benign prostatic hyperplasia, such as frequent urination, urgency, increased nocturia, waiting for urination, thinning of urine stream and feeling of incomplete urination, etc. It has a good alleviation effect especially on patients with incomplete urination.

Acute urinary retention prevention

Because for patients with a higher risk of acute urinary retention, silodosin can also be used as one of the important treatment options for prevention.

The pictures are from public channels (such as the official website of the FDA, the official website of the original drug manufacturer, etc.) and are for reference only.

The above content only reflects the scope of indications in the countries where the drug is registered overseas, and does not represent the scope of approved use in mainland China. Please consult a professional doctor for specific circumstances.

How to store silodosin after purchasing

Temperature control requirements

Silodosin should be stored at a room temperature of 20°C to 25°C. It is allowed to fluctuate between 15°C and 30°C when taken out for a short period of time.

Try to keep silodosin away from direct sunlight and high-temperature heat sources, such as radiators, stoves, etc., especially avoid placing it near the kitchen stove.

Light protection measures

Silodoxin should always be stored in the original packaging bottle, which is designed to protect against light.

Moisture-proof treatment method

Try to avoid bringing moisture into the medicine bottle and keep it in a sealed state.

Also avoid placing cotton or other dry materials in the medicine bottle with the tablets. These items absorb moisture and make the tablets more susceptible to moisture.

Expiration date management

Regularly check the validity period of drugs, and expired drugs should be disposed of in time. Do not continue to use expired medicines as their safety and effectiveness cannot be guaranteed. Local drug recycling guidelines should be followed when disposing of expired medications.

How to take Silodosin

Standard dosage and usage

1. Recommended dosage

According to its applicable dosage for adults, 8 mg once a day can achieve good therapeutic effects.

2. How to take the tablets

Try to take the tablets at the same time of the day. Please swallow the tablets whole according to the instructions on the package. Do not chew, crush or open the package without permission.

Methods for handling missed doses

If you forget to take a dose, you should take it as soon as you remember, unless it is close to the time for the next dose.

In this case the missed dose should be skipped and the medication should be continued as normal. Do not take a double dose to make up for a missed dose.

Guidelines for discontinuation of medication

Try to gradually reduce the original dosage of medication under the guidance of a doctor to avoid sudden discontinuation of medication. However, relapse often occurs relatively quickly after stopping the drug, so you should still communicate with your doctor about the follow-up treatment plan in a timely manner after stopping the drug.