非那雄胺中断一星期可以吗,停药会掉发得更厉害吗？

Losing more than 100 hairs per day in adults is called pathological alopecia. Pathological alopecia includes androgenic alopecia (AGA), alopecia areata (AA), alopecia folliculitis and discoid/systemic lupus erythematosus, among which AGA is the most common. The pathogenesis of AGA is not yet fully understood. It is related to the joint action of multiple factors, including androgen metabolism, inflammation in the surrounding environment, polygenic inheritance, mental factors, age, life and dietary factors, etc., and is usually accompanied by changes in the normal hair growth cycle (i.e. shortening of the growth phase and prolongation of the catagen and telogen phases). As we all know, it is very good at treating hair loss.

Finasteride is a synthetic 4-azasteroid compound and a 5ɑ-reductase inhibitor (5α-RIs) that acts as a competitive and specific inhibitor of dihydrotestosterone (DHT) receptors. The U.S. Food and Drug Administration (FDA) has approved oral finasteride for the treatment of AGA. FNS competitively inhibits the 5-alpha reductase type II enzyme, thereby preventing the conversion of testosterone into DHT, thereby effectively preventing androgen-dependent hair follicle miniaturization. So, is it okay to discontinue finasteride for a week? Will stopping the drug cause hair loss to become more severe?

Is it okay to interrupt finasteride for a week?

Typically, finasteride should be discontinued for a few days and things will go away. After taking finasteride, it can usually improve the symptoms of hair loss caused by excessive androgen secretion, and can also be used to prevent benign prostatic hyperplasia. During the period of medication, if it is interrupted for a few days, its therapeutic effect may be weakened. In addition, if the corresponding treatment is not given in time, it may even worsen the condition.

Will hair loss worsen if you stop taking finasteride?

Hair loss may worsen after discontinuing finasteride. The side effects of finasteride are mainly reflected in some negative obstacles to male function. Generally, the best effect is after one year of use. It is difficult to further improve hair loss if you insist on taking the medication, but hair loss will continue after stopping the medication.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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