What do burns mean to celebrities? Will the outcome be changed if collagenase ointment is used?

Introduction: , Common name: Collagenase, Trade name: Santyl Ointment. The drug is approved for debridement of chronic skin ulcers and severely burned areas.

In October 2010, a blockbuster news in the entertainment industry attracted people's attention. The famous singer Ren Jiaxuan (Selina) was rushed to the hospital for emergency treatment due to severe burns while filming. His fans flocked to the hospital to visit him, causing traffic jams for a while.

Before the burn, Ren Jiaxuan (Selina) was a hot star of that period. As a member of the female singing group S.H.E, she has developed in many fields with her sweet appearance. But after she came back from the burn, the heat was completely different from before. People said that the infection after the burn ruined her acting career.

Dangers caused by burns

Burns can cause huge damage to celebrities, as well as to ordinary people. It is estimated that burns cause the death of approximately 180,000 patients every year, and tens of millions of people require emergency medical treatment. The treatment situation cannot be underestimated.

In addition to affecting the appearance and the patient's mental health, burns can also cause local infection. Infections can gradually deepen the burned area and cause more tissue damage. In severe cases, it can damage organ function and threaten life. Collagenase ointment is a unique medicine suitable for debriding chronic skin ulcers and severely burned areas. Let’s follow the author to learn about this medicine.

Collagenase ointment mechanism of action

The threat of burns comes from the necrosis of wound tissue reaching the dermis. The persistence of necrotic tissue hinders epithelial crawling, and can also easily cause infection and aggravate inflammatory reactions, hindering wound repair. Scald wound repair is the top priority, and the first step is to remove necrotic tissue. Collagenase Ointment is a sterile enzymatic debridement ointment containing 250 collagenase units per gram of white petrolatum USP. The enzyme collagenase is derived from the fermentation of Clostridium histolyticum. It has the unique ability to digest collagen in necrotic tissue.

Since collagen makes up 75% of the dry weight of skin tissue, collagenase ointment's ability to digest collagen within physiological pH and temperature ranges makes it particularly effective at removing debris. Collagenase ointment facilitates the formation of granulation tissue and subsequent epithelialization of areas of dermal ulcers and severe burns without attacking the collagen in healthy tissue or newly formed granulation tissue.

Dosage and Administration

Collagenase ointment should be applied once daily (more frequently if the dressing becomes soiled, as in the case of urinary incontinence). When clinically indicated, remove as much loose debris as possible using forceps and scissors. Use collagenase ointment as follows:

1. Before use, gently rub the wound debris with a gauze pad containing normal saline solution or a cleanser compatible with collagenase ointment and then rinse with normal saline.

2. Whenever infection is present, it is best to use an appropriate topical antibiotic powder. Antibiotics should be applied to the wound ointment before applying collagenase ointment. If the infection does not respond, treatment with collagenase ointment should be discontinued until the infection resolves.

3. Collagenase ointment can be applied directly to the wound or on a sterile gauze pad, which is then applied to the wound and fixed correctly.

4. When the debridement of necrotic tissue is completed and the granulation tissue is well established, the ointment should be terminated.

Burns cause huge psychological and physical damage to patients. We must pay attention to fire safety in daily life, especially the protection of minors when using fire, to avoid the occurrence of burns. If burns occur, you should seek medical treatment as soon as possible to avoid further infection of the burns. Please pay attention to Medical Companion Travel, we will provide you with more health and safety knowledge.

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