利特昔替尼在中国能买到进口版的了吗?

An imported version of ritexitinib can be purchased in China.

Ritexitinib has been launched in China on October 18, 2023. The original drug was developed by Pfizer in the United States. It can be purchased in hospital pharmacies after it is launched in China. The several purchase methods currently known are roughly as follows:

1. Hospital pharmacy: Patients can purchase it directly at the hospital pharmacy after the doctor issues a prescription.

2. Online pharmacies: Many regular online pharmacies also provide sales services for ritexitinib. Patients can choose a reputable online pharmacy to purchase, but be sure to ensure the legality of the pharmacy and the authenticity of the medicines.

3. Regular overseas purchasing: For situations where ritexitinib may not be available directly in some areas, patients can obtain the drug through regular overseas purchasing services.

4. Official channels of pharmaceutical companies: Sometimes pharmaceutical companies will provide official purchase channels, and patients can purchase directly through the official website or customer service.

5. Clinical trial participation: In some cases, patients may have the opportunity to obtain the drug by participating in a clinical trial of ritexitinib. This usually requires certain conditions to be met and is done under the guidance of a doctor.

6. Overseas medical service institutions: Domestic professional and qualified overseas medical service institutions can also help patients obtain ritexitinib. They may cooperate with pharmacies at home and abroad, which can guarantee that it is genuine and mail the drug to their home, which is more cost-effective.

It is recommended to consult a doctor before purchasing to ensure that the medication is in line with your actual personal situation. In addition, you need to understand local and international regulations regarding drug purchase and use to ensure the legality of the drug purchase process.

About ritexitinib

In people with alopecia areata, the immune system attacks hair follicles, causing hair growth to slow down or stop completely, leading to hair loss. Ritexitinib is an immunosuppressant (a drug that reduces the activity of the immune system). It works by blocking the action of certain enzymes called JAK3 and TEC kinases, which play important roles in inflammation. By blocking these enzymes, ritexitinib reduces inflammation and allows hair to regrow in patients with alopecia areata.

Therapeutic Effects of Ritexitinib

The benefits of ritixitinib were investigated in one major study involving 718 adults and adolescents aged 12 years and older with severe alopecia areata, 261 of whom received 50 mg of ritixitinib or placebo (dummy treatment). All patients had more than 50% scalp hair loss before starting treatment.

After 24 weeks of treatment, patients treated with ritexitinib experienced improvement in disease symptoms: 13% of them were in near remission, meaning they had more than 90% hair coverage on their scalp, and 23% had more than 80% hair coverage. This improvement occurred in 1.5% of patients taking placebo. After 48 weeks, 31% of patients treated with ritexitinib were in near remission.

When asked whether their hair loss had improved, 49% of patients taking ritexitinib said their condition had improved moderately or greatly, compared with only 9% of patients taking placebo.

For more information about the safety of ritexitinib, please click: This article has a detailed introduction.

Summary

Ritexitinib is a drug used to treat severe alopecia areata in adults and adolescents over 12 years old. It is contraindicated during pregnancy. Before initiating treatment with rituxitinib, all immunizations should be updated according to current vaccination recommendations and administration of live-attenuated vaccines during or immediately before treatment should be avoided. It is recommended that patients take medication under the guidance of a doctor, treat symptoms, and not use it blindly.

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