迪高替尼软膏(Delgocitinib)现在多少钱一盒

Delgocitinib ointment, also known as Delgocitinib and CORECTIM, is suitable for the treatment of atopic dermatitis. It can improve skin inflammation, itching and related symptoms, regulate the function of the immune system, and exert a therapeutic effect.

How much does a box of Delgocitinib ointment cost now?

Delgocitinib ointment has not yet been approved for marketing in mainland China, nor has it been included in the medical insurance catalog. Currently, it is a Japanese original drug sold on the market with a specification of 0.25%*5g and a price of about US$96 per box. The specification is 0.5%*5g, and the price is about US$130 per box. Both specifications are 10 pieces per box.

The main reasons why Digotinib Ointment has not been launched in China include the approval process and the need for localized clinical trials. It is recommended that patients in need regularly pay attention to announcements from the drug regulatory authorities or obtain the latest developments through regular medical institutions.

Usage and dosage of Delgocitinib ointment

Standardized medication can control symptoms and reduce the chance of adverse reactions. Patients must strictly follow differentiated medication.

Usage specifications for adult patients

Adults should use 0.5% ointment twice a day. The amount of single application should not exceed 5 grams, and the coverage area should be less than 30% of the body surface. Clean and dry the affected area before use. Take a pea-sized amount of ointment and apply it gently until absorbed. If symptoms do not improve after 4 weeks of continuous use, you should contact your doctor to adjust the treatment plan. After symptoms are relieved, it is recommended to gradually reduce the frequency of medication to avoid long-term dependence.

Principles of medication adjustment for children

Children over 2 years old should use 0.25% concentration preparation twice a day, with no more than 5 grams per dose. Infants and young children aged 6 months to 2 years old need to control the dosage at 2.5 grams/time. Observe skin reactions every week during treatment. If redness and swelling worsen or new rash occurs, you should immediately switch to low-concentration preparations. It is recommended to follow up with your doctor every two weeks and adjust the dose based on your weight and body surface area.

Correct use of medication can reduce the chance of side effects. Next, we will focus on analyzing possible adverse reactions and countermeasures.

Does Delgocitinib ointment (Delgocitinib) cause side effects?

Most patients tolerate it well, but individual differences may lead to local or systemic reactions, and side effects need to be identified and dealt with in a timely manner.

Local skin irritation

Patients may experience burning sensation, erythema or itching at the application site. Mild symptoms can be relieved by shortening the duration of a single dose, such as once daily instead of twice. For persistent irritation, discontinue use for 3-5 days and use cold compress or moisturizing cream to repair the skin barrier. If there is exudation or ulceration, you need to seek medical attention to rule out the possibility of infection.

Folliculitis and secondary infection

The medicinal ingredients of Digotinib ointment may clog hair follicles and cause inflammatory papules. When local pustules are found, digotinib ointment should be stopped immediately, the affected area should be cleaned with normal saline every day, and antibiotic ointment should be applied externally. Severe infections need to be treated with oral antibiotics. After recovery, you need to wait 1 week before resuming the use of Digotinib ointment.

Management of allergic reactions

Rarely, urticaria or facial edema may occur. If such symptoms occur, the medication should be stopped immediately, antihistamines should be taken orally, and the remaining ointment should be washed thoroughly with water. If accompanied by difficulty breathing or a drop in blood pressure, emergency medical treatment is required for glucocorticoid injection treatment.

In daily care, keep the affected skin clean and dry, and avoid scratching and excessive cleaning. Wear loose-fitting cotton clothing to reduce friction and irritation. If long-term use is required, a mild moisturizer can be used to enhance the skin barrier function.