克立硼罗在中国上市了吗?好购买吗？

Introduction: Criborate is an anti-inflammatory, non-steroidal phosphodiesterase 4 inhibitor. By inhibiting intracellular PDE-4 activity, it increases the level of cyclic adenosine monophosphate, participates in the regulation of pro-inflammatory cell signaling pathways, and reduces the production of pro-inflammatory cytokines, thereby achieving the effect of controlling skin inflammatory reactions.

Criborole’s listing information in China

It has been officially launched in China and can be purchased directly in China. On July 29, 2020, Criborole was approved for marketing by the China National Food and Drug Administration. The approved indications are mild to severe atopic dermatitis aged 2 years and above. On August 3, 2023, Pfizer's cliboroxin indication was approved by the China Food and Drug Administration for marketing, and is used to treat children and adult patients with atopic dermatitis 3 months and older.

Purchase channels for criborole

You can refer to the following. No matter which drug purchasing channel you choose, you must ensure that the source of the drug is regular.

1. Hospital: Patients can go to the dermatology department of the local hospital for treatment, and the doctor will issue a prescription. They can purchase Criborole directly in the hospital pharmacy, and they can also use the medicine under the guidance of a doctor.

2. Physical pharmacies: Patients can go to local physical pharmacies to buy criborole. Usually pharmacies will sell criborole and can purchase it after presenting a medical prescription.

3. Clinics: Some large clinics may sell Criborole, and it can be purchased in the clinic after a doctor issues a prescription.

4. Medical service institutions: If you want to purchase the overseas version of criborole, you can purchase it through domestic medical service institutions. You can usually buy the required version of criborole.

Criborole Medication for Special Populations

1. Pregnant women: Pregnant women or women who may be pregnant should only be administered the drug when the benefits of treatment are considered to outweigh the risks.

2. Breastfeeding women: Considering the benefits of treatment and the benefits of breast milk nutrition, consider continuing or stopping breastfeeding.

3. Pediatric patients: Criborole should be used with caution in low birth weight infants, newborns and infants, and you can start with a low dose.

4. Patients with hepatic dysfunction: Increases in AST and ALT have been observed in patients with severe hepatic dysfunction using criborole.

5. Patients with complications/history: An increase in the number of syncopal attacks, convulsive attacks, and convulsive attacks has been observed in patients with severe organic brain lesions, epilepsy, convulsions, etc.