芦可替尼乳膏6岁儿童能使用吗？

Introduction: It is not recommended for children under 6 years old. For children as young as 6 years old, using this drug may pose unnecessary risks because their skin is delicate and their immune systems are not fully developed. Children's skin may absorb and react differently to the drug than adults, so ruxolitinib cream is not recommended for children 6 years of age. When children have skin problems, they should seek help from professional doctors and choose safer and more suitable drugs for treatment.

Atopic dermatitis

Ruxolitinib cream as a topical treatment has demonstrated its safety and efficacy in mild to moderate atopic dermatitis in pediatric patients aged 12 to 17 years. The drug's use in this age group is strongly supported based on evidence from the TRuE-AD1 and TRuE-AD2 studies. Among them, 92 children aged 12 to 17 years old with mild to moderate atopic dermatitis participated in the study. Importantly, the study results showed that no clinically meaningful differences in safety or effectiveness were observed between adults and pediatric subjects in this age group. This provides us with a reliable treatment option to address the problems of atopic dermatitis faced by children in this age group.

Non-pigmented vitiligo

The safety and effectiveness of ruxolitinib cream for topical treatment of non-pigmented vitiligo in children aged 12 to 17 years has been scientifically verified. The use of this drug in this age group is strongly supported by the results of two authoritative studies, TRuE-V1 and TRuE-V2. Among them, a total of 55 children with non-pigmented vitiligo aged between 12 and 17 participated in the study. The study showed no clinically meaningful differences in safety or effectiveness were found in either adults or these pediatric subjects. This discovery provides us with a safe and effective treatment option to help improve the symptoms of non-pigmented vitiligo in children in this age group.

However, it is worth noting that the therapeutic effect and safety of ruxolitinib cream for children under 12 years old with non-pigmented vitiligo and atopic dermatitis have not yet been determined. Therefore, before use, we need to conduct careful evaluation based on the specific situation of each child and the advice of professional doctors.