贝罗司他胶囊用药说明及注意事项

Capsule medication instructions and precautions

Common name: berotralstat

Product Name:Orladeyo

Full names: berotralstat capsules, Orladeyo, berotralstat, Orladeyo

Indications:

Berostat ORLADEYO is a plasma kallikrein inhibitor indicated for the prevention of hereditary angioedema (HAE) in adults and pediatric patients over 12 years of age.

Usage and dosage:

The recommended dose of berosostat is one capsule (150 mg) taken once daily with food.

Side effects:

Heart rhythm problems. Taking more than one Oradejo capsule a day may cause QT prolongation, a condition that causes an abnormal heartbeat.

The most common adverse reactions (≥10%) with Berostat Oladijo are abdominal pain, vomiting, diarrhea, back pain, and gastroesophageal reflux disease.

Less common side effects of Oradejo include abnormal liver function tests.

A less common side effect of Berostat Oladejo: A brief, itchy rash.

Things to note:

Risk of QT prolongation at higher than recommended doses: Berostat Orladeyo should not be used to treat acute exacerbations of HAE. Additional once daily doses or doses higher than 150 mg of Orladeyo are not recommended. A concentration-dependent increase in QT was observed at doses above the recommended daily dose of 150 mg.

Drug Interactions: Inform patients that Berostat Orladeyo may interact with other drugs. Advise patients to report the use of any other prescription or over-the-counter medications or herbal products to their physician.

Not indicated for the acute treatment of acute ischemic encephalopathy attacks: Advise patients to take commonly used rescue medications for the treatment of acute ischemic encephalopathy attacks. Inform patients that the safety and effectiveness of using Berostat orladeyo as an acute treatment for HAE attacks has not been established. Advise patients not to take daily doses of more than 150 mg or additional doses of Orladeyo once daily to treat acute attacks of HAE due to the risk of QT prolongation.

The above is the content of Berosstat’s instructions and precautions. I hope it can help you!

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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