奥拉迪约作用与功效

RESEARCH TRIANGLE PARK, N.C., Dec. 3, 2020 (GLOBE NEWSWIRE) -- BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX) today announced that the U.S. Food and Drug Administration (FDA) has approved oral, once-daily (berotralstat) for the prevention of the onset of hereditary angioedema (HAE) in adults and pediatric patients 12 years of age and older.

"Oradio provides HAE and its physicians with the first oral nonsteroidal drug to prevent HAE attacks, which is an important and welcome step in providing physicians and patients with more treatment options," said Anthony J. Castaldo, president and chief executive officer of the Hereditary Angioedema Association of America (HAEA).

Oradejo is a plasma kallikrein inhibitor that binds to plasma kallikrein and inhibits its proteolytic activity. Plasma kallikrein is a protease that cleaves high molecular weight kininogen (HMWK) to produce cleaved HMWK (cHMWK) and bradykinin, a potent vasodilator that increases vascular permeability, leading to the swelling and pain associated with HAE.

In patients with HAE due to C1 deficiency or dysfunction of the inhibitor (C1-INH), plasma kallikrein activity is not regulated normally, which leads to an uncontrolled increase in plasma kallikrein activity and leads to angioedema attack. Oladidate reduces plasma kallikrein activity to control excessive bradykinin production in hospitalized patients with HAE.

Currently (Orladeyo) is not listed in our country, so it is not eligible for medical insurance. In other words, if patients want to purchase the drug, they must go abroad to purchase it. Traveling abroad to buy medicines is a long journey and requires a lot of manpower and material resources. Coupled with the huge medical expenses, many patient families are overwhelmed. However, as far as Medical Companion Travel currently knows, Oladiyo is more cost-effective than other versions, and it is directly mailed overseas, which is convenient and fast, and 100% authentic. Since the exchange rate has been in a state of fluctuation for a long time, the price fluctuates with the exchange rate and is not static. For more information about Oradieu, please contact Medical Companion Travel for details.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.