氘可来昔替尼(Deucravacitinib)导致的不良反应怎么治疗？

Introduction: Deucravacitinib is a highly selective allosteric inhibitor of tyrosine kinase 2 (TYK2) that can inhibit key signaling pathways, reduce skin inflammation, and promote the regression of skin lesions and skin repair. Data from the POETYK PSO Long-Term Extension Trial (LTE) show that taking deuterated colexitinib for 16 weeks maintained its therapeutic response until 52 weeks.

Adverse reactions caused by Deucravacitinib

Possible adverse reactions mainly include the following.

1. Common adverse reactions: including upper respiratory tract infection, nasopharyngitis, cold sores, oral ulcers, folliculitis, and acne.

2. Allergic reactions: including fainting sensation, swelling of face, eyelids, lips, mouth, tongue or throat, difficulty breathing or throat tightening, chest tightness, rash or hives.

3. Other adverse reactions: including nausea, vomiting, diarrhea, rash, itching, impaired liver function, dizziness, fatigue and high blood pressure.

It may vary from person to person. Patients should pay close attention to these potential risks when using it, and promptly inform their doctor for treatment if side effects occur.

How to treat adverse reactions caused by Deucravacitinib

1. Upper respiratory tract infection: Patients should closely monitor signs of infection, such as cough, fever or sore throat, and use anti-infective drugs for control if necessary.

2. Gastrointestinal discomfort: These symptoms are usually mild and can be relieved by adjusting your diet. If the symptoms are more obvious, you should consult a doctor in time, and the medication method or dosage may need to be adjusted.

3. Headache: Patients can use over-the-counter pain relievers, such as acetaminophen or ibuprofen, to relieve headaches.

4. Skin reaction: Patients should keep their skin clean during medication and avoid excessive friction. If a more serious skin reaction occurs, you need to consult a doctor in time, and the medication regimen may need to be adjusted.

Patients should pay close attention to these potential risks during use and take a series of measures to improve them.

C) Patients should also be contraindicated in deuterated colexitinib.

The above are the main contraindications of deuterated colexitinib. Patients should fully communicate with medical professionals before use to ensure that there are no such contraindications.