罗氟司特乳膏的具体用法以及注意事项？

It is a white to off-white cream, suitable for patients with plaque psoriasis over 12 years old. It can be used on the skin (external use). The specific usage and precautions are as follows:

1. Patients need to take medication under the guidance of a doctor and are not allowed to use it privately to avoid improper use of medication that may affect their health.

2. ZORYVE needs to be applied to the affected area once a day. The cream needs to be rubbed in thoroughly until it is no longer visibleon the skin. Wash your hands after application, unless ZORYVE is used to treat hands.

1. ZORYVE is for local skin use only and is not for oral, ocular or intravaginal use.

2. Roflumilast cream should not be used in patients with moderate to severe liver damage. Oral roflumilast 250 mcg once daily for 14 days was studied in subjects with hepatic impairment. The results were increased AUC and Cmax values ​​for roflumilast and roflumilast N-oxide in subjects with moderate hepatic impairment.

3. Since it is currently unclear whether ZORYVE will affect the fetus, it is not recommended for people who are pregnant or planning to become pregnant.

4. Patients who are breastfeeding or planning to breastfeed should use with caution. It is not clear whether ZORYVE will enter breast milk. Therefore, you should consult your doctor to discuss the best way to breastfeed during treatment with ZORYVE.

Breastfeeding women using ZORYVE should apply it to the smallest area of skin and for the shortest period of time required. Do not apply the medication directly to the nipple or areola to avoid contact with the baby.

5. Since ZORYVE may interact with other drugs, such as erythromycin, ketoconazole, fluvoxamine, enoxacin, cimetidine and other 6.1 drugs that inhibit cytochrome P450 (CYP) enzymes, as well as 6.1 oral contraceptives containing gestodene and ethinyl estradiol, the above drugs should be avoided when using ZORYV to avoid an increase in adverse drug reactions.

During treatment with ZORYV, if patients need to take other medications, they should inform their healthcare provider in advance of the medications they are taking, including prescription and over-the-counter medications, vitamins, and herbal supplements.

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