服用甲氨蝶呤片过敏该怎么办

Indications:

1. Various types of acute leukemia, especially acute lymphoblastic leukemia, malignant lymphoma, non-Hodgkin's lymphoma, mycosis fungoides, and multiple myelopathy;

2. Head and neck cancer, lung cancer, various soft tissue sarcomas, and psoriasis;

3. Breast cancer, ovarian cancer, cervical cancer, malignant mole, chorioepithelial cancer, and testicular cancer.

Any medicine will have side effects. What should you do if you are allergic to methotrexate tablets? Under the guidance of a doctor, temporarily stop taking methotrexate tablets, take some anti-allergic drugs, and try not to scratch the area where the rash occurs to avoid infection.

Allergic reactions to methotrexate tablets are relatively rare in clinical practice. However, due to its important significance to the prognosis of patients, most of them cannot be abandoned and need to be continued. In order to prevent allergic reactions when using methotrexate tablets, a series of measures such as using anti-allergic drugs in advance under the guidance of a doctor, extending the infusion time, reducing the preparation concentration, and advancing the rescue time of leucovorin can be used to prevent the recurrence of allergic reactions.

Precautions when taking methotrexate tablets:

1. Methotrexate tablets are less mutagenic, teratogenic and carcinogenic than alkylating agents, but there is a potential risk of secondary tumors after long-term use;

2. Effects on reproductive function, which can lead to amenorrhea and sperm reduction or deficiency, especially after long-term use of larger doses, but are generally not serious and sometimes irreversible;

3. Methotrexate tablets are contraindicated in cases of extreme systemic failure, cachexia, concurrent infection, or heart, lung, liver, and kidney dysfunction. It should not be used when the peripheral blood count such as white blood cells is lower than 3500/mm3 or platelets is lower than 50000/mm3. Methotrexate tablets are Western medicines. Pregnant women should use methotrexate tablets with caution.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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