氯法齐明有什么副作用？吃多久可以停药？

Clofazimine is also called spiramycin, chlorphenazine, and clofazimine soft capsules. The trade name is clofazimine gelatin pills. It is the drug of choice for the treatment of tumor-type leprosy. It can also treat erythematous nodular leprosy reactions and acute leprosy reactions caused by other drugs. It has a slow bactericidal effect on Mycobacterium leprae and is also effective against Mycobacterium tuberculosis and Mycobacterium ulcerans when combined with other antimycobacterial drugs.

What are the side effects of clofazimine?

Red staining and pigmentation of the skin, red external eye conjunctiva, urine, sputum, and sweat, dry skin and ichthyosis-like changes, nausea, vomiting, anorexia, abdominal pain, constipation, diarrhea, drowsiness, dizziness, insomnia, etc. are common side effects of clofazimine. The patient's constitution and condition are different, and the manifestations of side effects are also different. This product is contraindicated in patients allergic to clofazimine, severe liver and kidney dysfunction, and gastrointestinal diseases. During treatment, you can pay more attention to your own reactions. If you have intolerance, contact your doctor in time for symptomatic treatment.

How long does it take to stop taking clofazimine?

When treating various types of leprosy that are resistant to dapsone, clofazimine should be taken at a dosage of 50-100 mg once a day. For the treatment of various types of leprosy with erythematous nodular leprosy reactions, and when there are ominous signs of nerve damage or skin ulcers, clofazimine should be taken at a dosage of 100-300 mg once a day. When taking more than 100mg of medication daily, it is necessary to closely observe the reaction after taking the medication, notify the doctor in time when symptoms subside, and shorten the course of high-dose medication as much as possible. Whether clofazimine can be stopped after taking it needs to be comprehensively judged by the doctor based on the patient's personal constitution and the severity of the condition. When using the drug, be sure to consult a doctor to avoid stopping the drug without permission, which may lead to aggravation of the disease. If the condition of tumor-type leprosy becomes stable after timely treatment in the early stage and the body is no longer susceptible, the medication can be stopped appropriately under the guidance of a doctor. However, patients with tumor-type leprosy are usually prone to type II leprosy reactions, which can lead to deformity and disability in severe cases. Therefore, patients are not recommended to stop taking the medicine privately to avoid adverse consequences and affect their recovery.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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