抗麻风病药物氯法齐明哪里买?康护乐告诉你氯法齐明购买渠道
When clofazimine is combined with dapsone, its anti-inflammatory effect is reduced, but its antibacterial effect is not affected. When clofazimine is used concomitantly with rifampicin, the absorption rate of rifampicin may be reduced and the time to peak absorption may be delayed. It not only has a slow bactericidal effect on Mycobacterium leprae, but is also effective against Mycobacterium tuberculosis and Mycobacterium ulcerans when combined with other antimycobacterial drugs. In addition, it also has anti-inflammatory effects and is effective in treating and preventing type II leprosy reactions such as nodular nodules and erythema multiforme. Today let’s find out where to buy the anti-leprosy drug clofazimine? Medical Companion Travel will tell you where to buy clofazimine.
Clofazimine has been included in the domestic medical insurance and can be purchased in hospital pharmacies, but the financial burden is heavy. If patients want to purchase clofazimine with a high cost performance, they can consult domestic professional overseas medical service companies (such as Medical Travel). Medicines are delivered directly to your doorstep and are guaranteed to be genuine. For specific prices, please consult the Medical Companion Travel Service.
There are also many:
Skin redness and pigmentation: the most common, usually appearing 2 to 4 weeks after taking the drug, and most obvious at 6 to 12 months. The skin will appear light red at first, and then turn from tan to purple-black, making the exposed parts more obvious. In addition, the conjunctiva, urine, sputum, and sweat all appear red. Clofazimine can pass through the placenta and enter breast milk, causing skin staining in newborns and infants. The degree of skin redness and pigmentation is directly proportional to the dose and course of treatment, and will gradually subside after stopping the drug.
Dry skin and ichthyosis-like changes: mostly appear 2 to 3 months after taking the drug, and are most obvious on the extended sides of the limbs (especially the lower limbs). They gradually subside about 3 months after stopping the drug. Topical emollients can alleviate the symptoms.
Gastrointestinal reactions: A few patients have adverse reactions such as nausea, vomiting, anorexia, abdominal pain, constipation and diarrhea, which are generally mild and do not affect treatment. Taking clofazimine with food can alleviate the symptoms. If the abdominal pain is severe, the medication should be discontinued.
Others: drowsiness, dizziness, insomnia, etc.
Clofazimine has multiple mechanisms of action against MTB. The most likely mechanism of action is by interfering with the nucleic acid metabolism of MTB, binding to its DNA, inhibiting DNA-dependent RNA polymerase, preventing RNA synthesis, thereby inhibiting bacterial protein synthesis and exerting its antibacterial effect. Less likely to develop resistance than other anti-tuberculosis drugs (1B).
Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.
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