埃索美拉唑治疗胃病可以吗

(Nexium) is the S-isomer of omeprazole. It reduces gastric acid secretion through a specific raking action mechanism and is a specific inhibitor of proton pumps in parietal cells. Site and mechanism of action: Esomeprazole (Nexium) is a weak base that is concentrated in the high-acid environment of parietal cell acid secretion microtubules and converted into an active form, thereby inhibiting H+/k+-ATP (proton pump) at this site, inhibiting both basic gastric acid secretion and stimulated gastric acid secretion. Today we will learn more about whether the Indian version of esomeprazole can treat stomach problems?

Esomeprazole (Nexium) is approved for 1. Gastroesophageal reflux disease (GERD): treatment of reflux esophagitis and long-term treatment to prevent recurrence in patients with cured esophagitis. 2. Combined with appropriate antibacterial therapy, it can eradicate Helicobacter pylori, heal duodenal ulcers related to Helicobacter pylori infection, and prevent the recurrence of peptic ulcers related to Helicobacter pylori infection. 3. Patients who require continuous NSAID treatment: gastric ulcer treatment related to the use of (nonsteroidal anti-inflammatory drugs) NSAID treatment.

Esomeprazole (Nexium) is available in oral and injection forms. For gastric and duodenal ulcers: 20 mg each time, taken once in the morning. The treatment course for duodenal ulcer is usually 2 to 4 weeks, and the treatment course for gastric ulcer is 4 to 8 weeks. For those with refractory ulcers, 20 mg twice a day or 40 mg once a day can be used. Although oral esomeprazole can achieve good clinical results, in some patients, such as patients with dysphagia, vomiting, acute upper gastrointestinal bleeding and patients recovering from major surgery, when used to treat peptic ulcer bleeding, 40 mg can be given intravenously, once every 12 hours, for 3 days. The first dose may be doubled. For patients with severe bleeding, intravenous infusion of 80 mg can be used for the first dose, and then maintained at 8 mg per hour until the bleeding stops.

In a clinical comparative study of esomeprazole (Nexium) and omeprazole in the treatment of reflux esophagitis, the total effective rate of esomeprazole was 97.18%, which was significantly higher than 84.51% of omeprazole, and there was no significant difference in the incidence of adverse reactions. Chen Caiming conducted a cost-effectiveness analysis of omeprazole and esomeprazole in the treatment of duodenal ulcer. The recovery rate of the esomeprazole group was 92.6%, which was higher than that of omeprazole, 78.6%. The results proved that esomeprazole has cost and effectiveness advantages.

The above is the content of the introduction of (Nexium) drugs, I hope it can help you!

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