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日本版埃索美拉唑效果怎么样

Author: Medicalhalo
Release time: 2025-10-19 11:44:20

It can effectively inhibit gastric acid secretion and is often used to treat diseases related to gastric acid secretion disorders, such as gastric ulcer, duodenal ulcer, etc. Esomeprazole is the S-isomer of omeprazole. It reduces gastric acid secretion through a specific targeting mechanism and is a specific inhibitor of proton pumps in parietal cells. Today we will learn more about the effectiveness of the Japanese version of esomeprazole?

Esomeprazole is the S-isomer of omeprazole. It reduces gastric acid secretion through a specific targeting mechanism and is a specific inhibitor of proton pumps in parietal cells. In a clinical comparative study of esomeprazole and omeprazole in the treatment of reflux esophagitis, the total effective rate of esomeprazole was 97.18%, which was significantly higher than 84.51% of omeprazole, and there was no significant difference in the incidence of adverse reactions. Chen Caiming conducted a cost-effectiveness analysis of omeprazole and esomeprazole in the treatment of duodenal ulcer. The recovery rate of the esomeprazole group was 92.6%, which was higher than that of omeprazole, 78.6%. The results proved that esomeprazole has cost and effectiveness advantages.

To observe the efficacy and safety of esomeprazole enteric-coated capsules in the treatment of duodenal ulcer. Methods 102 patients with duodenal ulcer admitted from December 2009 to February 2012 were selected as the research subjects. The patients were randomly divided into two groups. The experimental group (n=51) was treated with esomeprazole enteric-coated capsules, and the control group (n=51) was treated with esomeprazole tablets. The efficacy of the two groups of patients was observed and compared.

 

Results After treatment, the ulcer healing rate of patients in the experimental group was not significantly different from that of the control group, P>0.05; the symptom improvement rate of the experimental group was higher than that of the control group, and the clearance rate of Helicobacter pylori was higher than that of the control group, P<0.05. The difference was statistically significant; 5 patients in both the experimental group and the control group had adverse reactions, and the difference in the incidence of adverse reactions between the two groups was not significant and had no statistical significance (P>0.05). Conclusion: Esomeprazole enteric-coated capsules are effective in treating duodenal ulcer and are worthy of application in clinical work.  

Patients who have been treated with esomeprazole for a long time, especially those who have been using it for more than one year, are advised to go to the hospital for regular monitoring. For patients receiving on-demand treatment, it is best to contact their doctor if their symptoms and characteristics change. During the medication period, fluctuations in blood drug concentrations should be considered, which may cause drug interactions. When using esomeprazole to treat Helicobacter pylori, the effect of the ingredients in the triple therapy on the drug should be considered.

The above is the content of the treatment effect, I hope it can help you!

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