埃索美拉唑是治疗什么病症的？

What disease is it treating? Let’s find out together below. Esomeprazole is used for the treatment of gastroesophageal reflux disease (GERD), including the treatment of erosive reflux esophagitis, long-term maintenance treatment to prevent recurrence of cured esophagitis patients, and symptom control of gastroesophageal reflux disease (GERD). Esomeprazole combined with appropriate antimicrobial therapy can eradicate Helicobacter pylori, heal duodenal ulcers associated with Helicobacter pylori infection, and prevent the recurrence of peptic ulcers associated with Helicobacter pylori infection.

The main clinical manifestation of duodenal ulcer is upper abdominal pain, which can be dull pain, burning pain, distension or severe pain, or it can also present as dull pain and discomfort only when hungry. Typical cases present with mild or moderate persistent pain under the xiphoid process, which can be relieved by antacids or eating. Clinically, about 2/3 of the pain is rhythmic: epigastric pain begins 1 to 3 hours after breakfast, and will last until lunch if you do not take medicine or eat. The pain returns 2 to 4 hours after eating, but is relieved after eating. About half of the patients have midnight pain, and patients often wake up from the pain. Rhythmic pain usually lasts for several weeks and can recur after remission for several months.

The safety and effectiveness of esomeprazole treatment have been verified in two trials: a clinical comparative study of esomeprazole and omeprazole in the treatment of reflux esophagitis. The total effective rate of esomeprazole was 97.18%, which was significantly higher than that of omeprazole, which was 84.51%. There was no significant difference in the incidence of adverse reactions. Chen Caiming conducted a cost-effectiveness analysis of omeprazole and esomeprazole in the treatment of duodenal ulcer. The recovery rate of the esomeprazole group was 92.6%, which was higher than that of omeprazole, 78.6%. The results proved that esomeprazole has cost and effectiveness advantages. 

Clinical trials have also fully confirmed the excellent pH control ability of esomeprazole 40mg. In general, esomeprazole is very effective in treating early gastric cancer.

The above are the indications and clinical trial results provided by our Medical Companion Travel Overseas Medical Consulting Service Company.