阿瑞匹坦一次能囤几盒?多少钱?

This article will introduce in detail the stock quantity, price and efficacy of aprepitant. By exploring these aspects, we provide valuable reference information for patients and medical professionals. The article covers how many boxes of aprepitant can be stocked at one time, the prices of different versions, and its effectiveness in treating nausea and vomiting.

How many boxes of aprepitant can be stored at a time

Routine usage

According to clinical guidelines, adults and adolescents over 12 years old usually need to take aprepitant for three consecutive days when undergoing highly emetogenic chemotherapy (HEC) or moderately emetogenic chemotherapy (MEC). Take 125mg on the first day and 80mg on each of the following two days. Therefore, a single treatment session will require approximately a little more than a box of medication.

Consideration of long-term needs

For patients who require long-term chemotherapy, it is recommended to prepare sufficient drugs in advance according to the treatment plan. Considering that each box of aprepitant capsules contains 125mg*1 capsule + 80mg*2 capsules, it can meet the needs of one course of treatment. Therefore, if multiple courses of treatment are expected in the next few months, the stocking volume can be appropriately increased.

Storage conditions and validity period

Aprepitant capsules need to be stored at room temperature (20-25°C) and are valid for 24 months. Therefore, when hoarding, attention should be paid to checking the production date and ensuring that the storage environment meets the requirements to avoid drug failure.

How much does Aprepitant cost?

Indian Greenmark Pharmaceutical Factory Edition

The specifications of Aprepitant capsules produced by Greenmark Pharmaceutical Factory in India are 125mg*1 capsule + 80mg*2 capsules, and the price per box is about US$9. The price is relatively affordable and suitable for patients who need to take it for a long time.

Domestic generic version

In the domestic market, the first generic capsule "Oukeping" launched by Qilu Pharmaceutical and products from other manufacturers such as Zhengda Tianqing Pharmaceutical and Nanjing Entai Pharmaceutical have gradually entered the market. Due to competition from domestic generic drugs, the price has dropped compared to the original drug, but the specific price depends on local medical insurance policies and personal circumstances.

Price of injection dosage forms

Although the aprepitant injection developed by Heron Therapeutics has been approved abroad, it has not been widely used in China. Injections are relatively expensive and are mainly used for patients who are not suitable for oral medications.

Efficacy of aprepitant

Combination effect

Aprepitant is often used in combination with other antiemetics such as dexamethasone and 5-HT3 receptor antagonists to enhance the control effect on nausea and vomiting associated with highly emetogenic chemotherapy (HEC) and moderately emetogenic chemotherapy (MEC). This combination therapy significantly improves patient comfort and quality of life.

Effects on specific populations

Studies have shown that aprepitant is very effective in preventing nausea and vomiting associated with chemotherapy for the first or repeated courses in adults and adolescents aged ≥12 years. At the same time, the application of suspension dosage forms in children has also shown good tolerability and effectiveness. Suspensions offer another option for patients who are unable to swallow capsules.

Although aprepitant has significant efficacy, it may also cause a series of adverse reactions, such as fatigue, diarrhea, headache, etc. Therefore, patient response should be closely monitored during use and treatment regimens should be adjusted on a case-by-case basis.