昂丹司琼孕妇可以用吗,副作用及禁忌是什么？

Ondansetron tablets are anti-tumor auxiliary drugs that can prevent and treat nausea and vomiting symptoms caused by cytotoxic chemotherapy drugs and radiotherapy. It can also be used to prevent and treat nausea and vomiting symptoms after surgery. It is a highly selective 5-hydroxytryptamine (5-HT3) receptor antagonist. So, can ondansetron be used by pregnant women? What are the side effects and contraindications?

Can ondansetron be used by pregnant women?

Like other drugs, ondansetron should not be used during pregnancy, especially during the first trimester, unless the benefits to the patient outweigh any possible risks to the fetus. Ondansetron! In animal experimental studies, no direct or indirect harm to the embryo, fetus, pregnancy, perinatal period and postpartum period was found. The safety of ondansetron tablets for human pregnancy has not yet been determined. Pregnant women should use it with caution.

What are the side effects and contraindications of ondansetron?

Symptoms include epilepsy, headache, chest pain, constipation, warmth in the head or upper abdomen, bronchial asthma, ataxia, hypotension and other symptoms. The patient's condition and constitution are different, and the manifestations of side effects are also different. In addition, liver function damage, dry stool, headache, dizziness, tachycardia, and chest discomfort are also side effects of ondansetron, but they are rare, usually transient, and do not require special treatment.

Contraindications to the use of ondansetron in patients include patients with gastrointestinal obstruction, patients with hypersensitivity (e.g., anaphylaxis) to ondansetron or any component of the preparation, and concurrent use with apomorphine.

Chemotherapy and radiotherapy can cause vomiting in patients because they stimulate the release of 5-HT in the small intestine, and 5-HT3 can trigger the vomiting reflex through neurotransmission. Ondansetron exerts its antiemetic effect by antagonizing 5-HT receptors on neurons located locally in the peripheral and central nervous system. The above is about whether ondansetron can be used by pregnant women and what its side effects and contraindications are. I hope it can help you!

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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