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阿瑞匹坦治疗效果怎么样?阿瑞匹坦副作用是什么?

Author: Medicalhalo
Release time: 2025-10-19 11:44:20

Aprepitant is a gray-white to light yellow crystal-like solid chemical. It is mainly used clinically to prevent acute and delayed nausea and vomiting that occur during initial and repeated treatments of highly emetogenic anti-tumor chemotherapy. It is a neurokinin-1 receptor blocker with high selectivity and affinity.

So, how effective is aprepitant treatment?

Objective: To explore the antiemetic effect of aprepitant in patients with advanced breast cancer receiving chemotherapy. Methods: 80 breast cancer patients admitted for chemotherapy were randomly divided into a study group (40 cases) and a control group (40 cases). Both groups were given chemotherapy treatment. During the period, the control group was given an antiemetic regimen of granisetron + dexamethasone. On the basis of the control group, the research group added aprepitant for antiemetics, and the antiemetic effects of the two groups were observed. Results The total incidence rate of nausea and vomiting in the study group was 7.50%, which was significantly lower than the total incidence rate of 27.50% in the control group (P<0.05). Conclusion For breast cancer patients undergoing chemotherapy, the use of aprepitant can achieve good antiemetic effects and is worthy of promotion.

So, what are the side effects of aprepitant?

The side effects of aprepitant capsules include constipation, loss of appetite, increased blood sugar levels, increased blood creatinine, increased blood potassium, increased blood urea, neutropenia, proteinuria, etc. Aprepitant capsules can be taken with or without food. Side effects may vary depending on the condition and constitution. It is recommended that patients consult a doctor for details and use it under the guidance of a doctor.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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