美沙拉秦(Salofalk)怎么购买

Mesalazine is developed and produced by the German company Dr. Falk Pharma GmbH, which sells its brand Salofalk globally.

How to buy mesalazine (Salofalk)

1. Hospital pharmacy

After the hospital doctor diagnoses and issues a prescription, you can pay directly at the hospital outpatient pharmacy. This is the most common and recommended way to purchase medicine.

2. Physical chain pharmacies

It is recommended to choose large and well-known chain pharmacies, where you can obtain medicines after presenting a prescription. When purchasing, be sure to check the batch number, expiration date and integrity of the outer packaging of the drug.

3. Compliant online medical platform

After the doctor issues an electronic prescription and places an order at the platform’s online pharmacy, be sure to choose an official pharmacy with clear signs that is self-operated or certified by the platform, and be wary of any merchants that sell prescription drugs without a prescription.

Therapeutic effect of Mesalazine (Salofalk)

Mesalazine (Salofalk) enteric-coated tablets have been shown in clinical studies to be effective in inducing remission and maintaining treatment in the acute phase of mild to moderate ulcerative colitis and Crohn's ileitis and colitis.

The mechanism of action of mesalazine is mainly through local anti-inflammatory effects, including inhibiting inflammatory mediators, regulating prostaglandin and leukotriene levels, and having oxygen free radical scavenging effects.

The pictures are from public channels (such as the official website of the FDA, the official website of the original drug manufacturer, etc.) and are for reference only.

Mesalazine (Salofalk) drug interactions

1. Anticoagulants (such as warfarin)

Mesalazine may enhance its anticoagulant effect and significantly increase the risk of bleeding.

2. Antidiabetic drugs (such as glibenclamide)

may enhance the hypoglycemic effect and cause hypoglycemia. Blood glucose monitoring needs to be strengthened and the dosage of antidiabetic drugs should be adjusted in a timely manner.

3. Immunosuppressants (such as azathioprine, 6-mercaptopurine)

Combined use may enhance bone marrow suppression and significantly increase the risk of leukopenia and thrombocytopenia, and blood routine must be closely monitored.

4. Rifampicin

may weaken the anti-tuberculosis effect.

5. Diuretics (such as spironolactone, furosemide)

Mesalazine may weaken the diuretic effect.

6. Drugs that promote uric acid excretion (such as probenecid)

may affect their uric acid-lowering effect.

7. Lactulose

Such drugs that lower intestinal pH may destroy the integrity of the enteric coating of mesalazine, causing premature release of the drug in the stomach, affecting its targeted delivery effect and increasing gastric irritation.

8. Glucocorticoids (such as prednisone)

may increase the irritation to the gastrointestinal tract.

9. Methotrexate

Combined use may increase the hematological toxicity and hepatotoxicity of methotrexate.

Mesalazine (Salofalk) overdose

1. Symptoms

Nausea, vomiting, diarrhea, and salicylic acid poisoning-like symptoms.

2. Treatment

There is no specific antidote, and symptomatic and supportive treatment is recommended.