布地奈德缓释胶囊是什么药？怎么使用？

Budesonide sustained-release capsules developed by Calliditas were approved by the FDA for marketing in 2021. Their affinity for the glucocorticoid receptor reflects the intrinsic potency of the drug and is 200 times greater than that of cortisol. Today let’s take a closer look at what budesonide sustained-release capsules are? How to use?

Budesonide sustained-release capsule is an anti-inflammatory corticosteroid with high glucocorticoid effect and weak mineralocorticoid effect. The advantage of this drug is that it is used locally on the lesion, and only a small amount of the drug will be absorbed into the blood circulation system, so it is safer. The drug is mainly used for mild to moderately active Crohn's disease. It has also completed phase II clinical studies for IgA nephropathy and has been granted orphan drug status by the European Union and the US FDA. Flatulence, headache, respiratory infection, nausea, indigestion, dizziness, abdominal pain, back pain, vomiting, fatigue and pain are the main side effects, but overall safety is controllable.

The dosage for pediatric patients 8 to 17 years old with mild to moderate active Crohn's disease and weighing more than 25 kg is: 9 mg once daily for up to 8 weeks, then 6 mg once daily for 2 weeks. For adults, the treatment process is repeated for 8 weeks, 9 mg per day, and up to 8 weeks; for adults: 6 mg per day, up to 3 months, and stopping after 3 months of tapering is used to maintain clinical remission of mild to moderate Crohn's disease. Patients should follow the doctor's instructions and read the instructions carefully. Do not change the dosage and usage at will, so as not to affect the effect of the drug and cause intolerance reactions. Patients should also note that use is prohibited for patients allergic to budesonide ingredients.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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