兰索拉唑是什么药？治疗什么病？

What kind of medicine is lansoprazole? What disease is treated? Lansoprazole is a new type of proton pump inhibitor (PPI). Its advantage in inhibiting gastric acid secretion is that it can continuously increase the pH value in the stomach, has stronger acid-suppressing effect, has a rapid onset of action, and can maintain a high acid-suppressing level throughout the day. It has the advantages of high cure rate, faster symptom relief, and fewer side effects. Injection can be used for the treatment of duodenal ulcers with bleeding, gastric ulcers with bleeding, acute stress ulcers and acute gastric mucosal lesions that are not suitable for oral therapy.

Lansoprazole was first reported in 1986. It is a new generation of proton pump inhibitor following omeprazole. In order for the drug to form an active form, it must combine with the proton pump under acidic conditions to exert its effect. This avoids the phenomenon of excessive acid suppression. The molecular structure of lansoprazole belongs to the benzimidazole class. It has strong binding affinity to Cys321 in the 3rd transmembrane region, Cys813 (or 822) in the 4th to 6th transmembrane region, and Cys892 in the 7th to 8th transmembrane region of H+-K+-ATPase. It can penetrate the parietal cell membrane and be converted into two derivatives, sulfenic acid and sulfenyl, and inhibit the secretion of gastric acid by gastric parietal cells, reducing p H value, inhibits the reproduction and activity of Hp.

In 2008, Jiangsu Aosaikang Pharmaceutical developed and launched injectable powder, and finally included the proton pump inhibitor lansoprazole in the "National Medical Insurance Drug Catalog" in 2017 to provide everyone with discounts. But even if they are covered by medical insurance, the price is still too high for most families to reach, and they have to choose to purchase drugs overseas to find drugs. Traveling abroad requires a lot of manpower, material and financial resources, and medical expenses are still quite large. However, as far as medical companions know, lansoprazole is more cost-effective than other versions, and it is shipped directly from overseas, which is convenient and fast, and 100% authentic. Since the exchange rate has been in a state of fluctuation for a long time, the price fluctuates with the exchange rate and is not static. For more information about lansoprazole, please contact Medical Companion Travel for details.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.