达那唑吃完皮肤发红、长痘痘怎么办？

Causes of red skin and acne

The patient's skin redness and acne after taking danazol are caused by the drug. Androgen-like effects include acne and seborrhea, weight gain, and skin flushing may reflect reduced estrogen levels.

In addition, patients may experience menstrual disorders (including spotting, changes in menstrual cycle timing, and amenorrhea), sweating, vaginal dryness and irritation, and breast reduction, nervousness and emotional instability, increased blood pressure, musculoskeletal pain, dizziness, nausea, vomiting, constipation, and abnormalities in semen volume, viscosity, sperm count, and motility.

Treatment method

If the patient's symptoms of skin redness and acne are mild after taking the medication, he can wash his face with water and avoid using irritating cleaning products, skin care products, and cosmetics. Instead, he can use mild skin care products, pay attention to skin moisturization, and pay attention to sun protection. At the same time, he can use adapalene gel, erythromycin ointment and other drugs to relieve symptoms.

During normal medication treatment, you should pay attention to a light diet and avoid eating spicy and greasy foods such as peppers, Malatang, barbecue, fried skewers, mustard, etc. to avoid aggravating skin damage. You can eat more fresh fruits and vegetables such as kiwi, apple, spinach, watermelon, etc., which will help to supplement the vitamins and other nutrients needed by the body and help improve the skin condition.

If the patient's skin becomes red and the acne is severe, he or she can consult a doctor in time and stop taking the medication or switch to other medications under the guidance of the doctor. The patient can also use metronidazole and other medications as directed by the doctor.

Mechanism of action and effect

Danazol is a synthetic, attenuated androgen that may interfere with the normal interaction between the pituitary-hypothalamic axis and the gonads. These effects are mediated by complex mechanisms, including that danazol can compete with natural steroids, bind to the androgen receptor or sex hormone-binding globulin, potentially displace the natural steroid in this protein, and bind to the active sites of enzymes required for the synthesis of natural steroids, thereby inhibiting synthesis.

Because danazol disrupts pituitary-hypothalamic interactions with the gonads, it is an effective drug in the treatment of endometriosis and cystic breast disease.

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