Side effects of dienogest in treating endometriosis

Dienogest is a new type of selective progesterone receptor agonist that can inhibit ovarian function and endometrial cell proliferation, thereby reducing the pain associated with EMs and shrinking and shrinking the lesions. Many international clinical research data show that it can effectively relieve EMs pain, reduce endometriosis lesions, and has good safety and tolerability. Today let’s learn about the side effects of dienogest in treating endometriosis.

The most common side effects of dienogest are headache, breast discomfort, including breast swelling, and breast pain. Adverse effects such as irregular bleeding are more common during the first few months of treatment with Visanin and gradually disappear as treatment continues.

Dienogest has no serious life-threatening side effects. Common side effects include amenorrhea, irregular bleeding, headache, chest discomfort, depression and acne, and can be recovered after stopping the medication.

Dienogest is a new type of progestin, also known as the fourth generation progestin. It is mainly used to treat endometriosis and adenomyosis. Dienogest is generally taken from 2-5 days into the menstrual cycle. It is actually a preparation for contraceptives and a mixed progestin. It has the pharmacological characteristics of both natural and synthetic progestins and has very high progesterone activity. Sex, it is very easy to combine with progesterone receptors, so the activity of estrogen and androgen is very low, making it an ideal progesterone preparation. Therefore, dienogest has been very eye-catching since it came out. It has a very good effect on the pain of heterotopia. It is suitable for the long-term management of heterotopia and an alternative treatment method to non-surgical treatment, preventing postoperative recurrence.

Dienogest plays a role in endometriosis by reducing the endogenous production of estradiol, thereby inhibiting the stimulating effect of estradiol on normal and ectopic endometrium. When administered continuously, it leads to an endocrine environment of low estrogen and high progesterone, causing decidualization of endometrial tissue, thereby shrinking endometriosis lesions.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.