Dienogest is a special progestin

Dienogest is a selective progesterone drug newly launched in recent years. In May 2019, dienogest was officially approved for marketing in my country. A number of clinical trials have confirmed that it has a certain effect on endometriosis. It is a newly developed high-efficiency synthetic progesterone. This drug is a highly selective progesterone receptor agonist. It is widely used in the clinical treatment of endometriosis, and its clinical efficacy has been confirmed by clinical practice.

Dienogest is a 19-nortestosterone derivative. It has the pharmacological advantages of both natural and synthetic progestins. It has a potent progesterone-like effect on the endometrium and only binds to progesterone receptors. It has no estrogenic, anti-estrogenic and androgenic activities. It has the effect of slightly inhibiting ovulation and reducing estrogen levels. Long-term use of dienogest can produce an endocrine environment of low estrogen and high progesterone, causing ectopic endometrium to atrophy. In addition, dienogest can inhibit the proliferation of endometrial cells, reduce the expression of nerve growth factor and nerve fiber density, and relieve pain symptoms.

For oral administration, take one tablet daily without interruption, preferably at the same time every day. Take the medicine with water when necessary. Common side effects of this drug are depression, amenorrhea, chest discomfort, irregular bleeding, acne, headache, breast discomfort, etc. Finally, the editor of Medical Companion Travel would like to give a reminder to all patients who are currently using dienogest. There are many rumors on the Internet saying that better effects can be obtained by increasing the dose of the drug. There are also claims that the dose of the drug can be reduced when the side effects are unbearable. These are all wrong. Only by following the doctor's instructions can the drug itself be used to its maximum effect.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.