打去纤苷有什么副作用?
What are the side effects of taking defibrinoside? (Defibrotide) also produces some side effects when used. The most common side effects (incidence ≥10% and independent causal relationship) with defibrotide treatment are hypotension, diarrhea, vomiting, nausea and epistaxis. The incidence of grade 3-4 reactions related to defibrotide was 7%, mainly hypotension, pulmonary and gastrointestinal bleeding, and abdominal cramps. Only 4% of patients discontinued treatment due to side effects. In other words, the side effects of defibrotide are usually mild, and patients do not need to worry too much.
It is important to note that defibrotide may enhance the pharmacodynamic activity of antithrombotic/fibrinolytic drugs such as heparin or alteplase. Concomitant use of defibrotide with antithrombotic or fibrinolytic drugs is contraindicated due to an increased risk of bleeding. Do not initiate defibrotide in patients with active bleeding. Monitor patients for signs of bleeding. If a patient bleeds while taking defibrotide, discontinue defibrotide, treat the cause, and provide supportive care until bleeding has stopped.
It is not currently on the market in China, so it will not be included in China's medical insurance catalog to provide everyone with preferential medical insurance policies. Patients who want to purchase defibrotide can only go abroad to purchase defibrotide at their own expense. However, as we all know, the price of original drugs is very expensive, and a lot of manpower and material resources are consumed in the process of purchasing drugs, which puts huge pressure on patients. Therefore, more people choose to purchase drugs overseas to obtain the drugs they need. According to what Medical Companion Travel currently knows, the specification of defibrinoside is 200 mg, and the price is about $21,600. It is more suitable for patients to use for a long time, is high quality and low price, and saves worry and effort. The exchange rate in the market often fluctuates, and the price is not always fixed, but will change with the exchange rate. For more information about defibrotide, please contact Medical Travel for details.
Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.
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