去纤苷治疗效果怎么样？可以用医保购买吗？

Defibrotide is currently recognized as the most promising new drug for the treatment of hepatic veno-occlusive disease (HVOD) after hematopoietic stem cell transplantation (HSCT). It is also called defibrotide sodium, defibrinoside sodium, and the trade name is Defitelio. It is an adenosine receptor agonist with multiple effects, including anticoagulation, fibrinolysis promotion, and anti-inflammatory effects.

In a phase 2 trial of 75 patients, 44% survived 100 days after transplantation. In a phase 3 trial of 102 patients, 38% survived 100 days after transplantation. In an additional 351 In expanded trials of patients, 45% survived 100 days after transplantation, all of whom were diagnosed with hepatic veno-occlusive disease (HVOD) and associated renal or pulmonary dysfunction after hematopoietic stem cell transplantation (HSCT). The estimated 100-day survival rate for patients with severe hepatic veno-occlusive disease (HVOD) without defibrotide treatment is 21%-31%. It can be seen that defibrotide has a significant effect in the treatment of hepatic veno-occlusive disease (HVOD). The use of this drug effectively prolongs the survival time of patients and has a positive effect on the patient's condition.

Can defibrotide be purchased with medical insurance?

Defibrotide is not currently on the market in China, and it cannot be purchased in domestic hospital pharmacies, let alone reimbursed by medical insurance. Patients who need it can go abroad to purchase it, but the risks and costs will increase. Patients can also use Medical Companion Travel to learn about defibrinosides delivered directly to their homes by overseas pharmaceutical companies. This ensures that the drugs are genuine and at an affordable price, which can reduce the financial burden on patients. Patients who want to know the specific price and purchase method of defibrinoside can consult the medical companion travel service. Drug prices are not fixed due to exchange rate fluctuations. It is not recommended for patients to use purchasing agents as they are easily deceived.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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