去纤维钠2020价格

Approved for marketing in the EU in October 2013, it is also called defibrinoside. After Gentium Pharmaceuticals was acquired by American Jazz Pharmaceuticals, defibrotide sodium was approved by the U.S. Food and Drug Administration (FDA) for marketing in the United States on March 30, 2016. This is the first drug approved by the FDA for the treatment of severe hepatic venule occlusion, a rare and fatal liver disease.

Defibrotide sodium is a new drug used to treat hepatic veno-occlusive disease, and its price has always been a matter of great concern. It is understood that defibrotide sodium is not currently on the market in my country. The overseas version of defibrinated sodium is equivalent to about $22,000 in RMB. If it is inconvenient for patients to go abroad, they can consult our Medical Companion Travel Overseas Medical Consulting Service Company to learn how to purchase it.

The approval of defibrotide was based on a phase 2 trial of 75 patients, a phase 3 trial of 102 patients, and an expanded trial of an additional 351 patients. The patients in these three trials were all diagnosed with hepatic veno-occlusive disease and associated renal or pulmonary dysfunction after HSCT (hematopoietic stem cell transplantation). Patients treated with defibrinated sodium survived 100 days after transplantation in 44% of patients in the phase 2 trial, 38% in the phase 3 trial, and 45% in the expanded trial, and the FDA noted in a report that the expected 100-day survival rate for patients with severe hepatic veno-occlusive disease who were not treated with defibrinated sodium was 21% to 31%. In other words, the use of defibrinated sodium will effectively improve the survival rate of patients.

Hepatic veno-occlusive disease (HVOD), also known as sinusoidal obstruction syndrome (SOS), is one of the serious complications after hematopoietic stem cell transplantation (HSCT). (Defibrotide) is currently awarded the title of orphan drug by the FDA. Its listing has brought new treatment options to patients. If you have other questions about purchasing drugs, you can also consult the medical companion travel service for answers.