febuxostat的价格是多少

febuxostat is a new, highly effective and selective inhibitor of non-purine xanthine oxidase, a key enzyme that promotes uric acid production. febuxostat is the latest XOR inhibitor developed in the world. It acts highly selectively on this oxidase to reduce the synthesis of uric acid in the body and reduce the concentration of uric acid, thereby effectively treating gout. 

Among drugs that inhibit uric acid production, colchicine is mainly used in the acute phase (acute phase) of the disease. Compared with febuxostat (febuxostat), it is mainly allopurinol. Compared with allopurinol, febuxostat (febuxostat) has the following advantages in addition to small side effects: 1. Allopurinol only inhibits the reduced form of XOR, while febuxostat (febuxostat) has a significant inhibitory effect on both oxidized and reduced forms of XOR, so its effect in reducing uric acid is more powerful and lasting; 2. Since allopurinol is a purine analogue, it inevitably affects the activities of other enzymes involved in purine and pyridine metabolism. Therefore, repeated high-dose administration is required to maintain high drug levels during allopurinol treatment. This also leads to serious or even fatal adverse reactions due to drug accumulation. Febuxostat is a non-purine XOR inhibitor and therefore has a better safety profile.

What is the price of febuxostat in India?

According to Medical Companion Travel, febuxostat has been launched in China, but because it is an imported original drug, it is expensive and many patients cannot afford it. The price of feburic (Febuxostat) on the domestic market is 10$ per tablet, 40mg/tablet, and the recommended dosage is 40mg/day, which costs about $300 a month. Patients with poor absorption of febuxostat may need to increase the dosage to 80mg/day, which means they need two tablets a day, which costs about $600 a month.

If patients cannot afford the domestic sales price of febuxostat, they can purchase the generic drug febuxostat produced by Zydus Pharmaceuticals in India. The price is relatively affordable and is the version most purchased by patients. The Indian generic febuxostat specification is 80mg*30 tablets/box, and its price is about $200.