uloric价格

(Febuxostat) is a new non-purine xanthine oxidase (XO) selective inhibitor that works by reducing blood urate concentration. It is completely absorbed orally and has a high utilization rate. Food and antacids have no significant effect on its absorption. Unlike allopurinol, its structure is a non-purine analogue, so it is selective in inhibiting xanthine oxidase and has little effect on other enzymes in purine or pyrimidine metabolism. In other words, Uloric (febuxostat) is less likely to be affected by other factors and has a stable effect. Uloric (febuxostat) is indicated for hyperuricemic gout, but not for urate-deficient gout.

Uloric (Febuxostat) mechanism of action: Uloric (Febuxostat) is rapidly and extensively absorbed by >80% after oral administration, with a tmax of approximately 1.0 to 1.8 hours. Febuxostat does not accumulate in the body after multiple oral doses of febuxostat administered daily. The effect of taking Uloric (Febuxostat) 80 mg multiple times to reduce serum uric acid concentration is not affected by food, so Uloric (Febuxostat) can be taken without considering food factors in clinical administration. The steady-state apparent volume of distribution (Vss/F) of Uloric (febuxostat) after oral administration of 10 mg to 300 mg is 29 to 75 L. Uloric (febuxostat) is approximately 99.2% plasma protein bound (mainly to albumin). Four hours after oral administration of Uloric (febuxostat), unchanged drug in the plasma accounted for 84%-96% of the total radioactivity. The plasma half-life of Uloric (febuxostat) is 5 to 8 hours, and steady-state plasma concentrations will be reached within 1 week after taking the drug once a day. Uloric (febuxostat) is mainly eliminated from the blood by being metabolized by the liver to glucuronide conjugates, and a smaller amount is oxidatively metabolized by CYP450 in the liver. Glucuronide-conjugated Uloric (Febuxostat) is excreted in the urine, and less than 4% of Uloric (Febuxostat) is excreted unchanged in the urine after oral administration.

What is the price of uloric?

The price of original medicine in Japan is higher than that in India, about 1,500$ per box. The efficacy of (Febuxostat) produced by Zydus Pharmaceuticals in India is the same as that of the original drug, and the price is relatively affordable. The specification is 80mg*30 tablets/box. Its price is about 200$. Due to the floating exchange rate, the price cannot be accurate. For specific prices, please consult the regular overseas medical service company Medical Travel.