What are the side effects of canakinumab and how long does it take for them to disappear after stopping the drug?

Canakinumab is a monoclonal antibody that neutralizes IL-1β. The CANTOS study found that among 10,061 subjects, patients who received 150 mg treatment reduced the primary endpoint of myocardial infarction or death from cardiovascular disease by 15% compared with placebo. It was also found that the 150 mg canakinumab group could also reduce the incidence of coronary revascularization and significantly reduce all-cause mortality from cardiovascular disease. In addition, among patients who received canakinumab for 4 years, the high-sensitivity C-reactive protein in the experimental group was reduced by 26%-41% compared with the placebo group. At the same time, the incidence of cardiovascular events was also significantly reduced. So, what are the side effects of canakinumab and how long does it take for them to disappear after stopping the drug?

What are the side effects of canakinumab?

: Headache, influenza, rhinitis, decreased calcium, increased eosinophils, dizziness, injection site pain, weight gain, bronchitis, elevated ALT (alanine aminotransferase), increased bilirubin, diarrhea, gastroenteritis, creatinine clearance, proteinuria, nausea, pharyngitis, allergic reaction, musculoskeletal pain, nasopharyngitis, etc.

How long does it take for side effects to disappear after stopping canakinumab?

Normally, you will recover slowly within 2 to 4 weeks after stopping the medication. Usually, obvious symptoms and side effects will disappear within a week after stopping the medication. The editor of Medical Companion Travel finally recommends that patients should follow the doctor's instructions and take the correct medication. Everyone's physical fitness and condition are different. A doctor should formulate the most accurate medication plan based on your test results. Do not change the dosage and medication time on your own to avoid delaying your own treatment.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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