Is there a generic version of Bezotivan on the market? Is it expensive?

Belzutifan As aHIF-2α inhibitor, it is a newer class of innovative drugs worldwide. It is mainly used to treat a variety of tumors related to von Hippel-Lindau disease (VHL), including clear cell renal cell carcinoma (RCC), retinal hemangioblastoma, central nervous system tumors, etc. The original research product has been launched by Merck and has been approved in many countries such as the United States, Japan, the European Union and China. Due to its novel targeting mechanism, scarce indications, and clear therapeutic effect, bezotivan has quickly become one of the important options in the treatment of hereditary tumors.

Regarding the issue of price and generic drugs, since the original drug of bezotivan is a newly launched product, the price is generally higher globally. In China, although the drug has been approved, it has not yet been included in the medical insurance catalog, so the overall drug purchase cost is still high for ordinary patients. However, some overseas pharmaceutical companies, especially represented by Laos, have launched generic versions with the same ingredients, including 40mg*90 tablets of generic drugs produced by Lucius Pharmaceutical Factory, Daxiong Pharmaceutical Factory and other companies. The price is mostly less than about one-third of the price of the original drug, floating around RMB 5,000. The specific price varies depending on exchange rates and channels.

It is worth emphasizing that although generic drugs strive to be consistent with the original drugs in terms of ingredients and bioequivalence, there are still gaps in clinical trial support, drug supervision, production technology and traceability guarantees. Therefore, when considering using overseas generic drugs, patients should obtain them through formal channels and use them under the guidance of a doctor to ensure controllable safety and efficacy. Some generic versions may also have problems such as incomplete specifications and inconsistent packaging. When purchasing, you need to clarify the source of the drug and verify the production batch number and authorization information.

Reference materials:https://www.welireg.com/