What are the side effects of Glecaprevir/pibrentasvir?

Glecaprevir/pibrentasvir tablets (Glecaprevir/pibrentasvir) is an antiviral drug used to treat chronic hepatitis C virus (HCV). It is suitable for adults and children over 3 years old.丙型肝炎是一种由丙型肝炎病毒引起的传染病，主要影响肝脏。 The mechanism of action of glecaprevir and pibrentasvir tablets is achieved through its active ingredientsglecaprevir and pibrentasvir. The former inhibits the NS3/4A protease of the virus, and the latter exerts antiviral effects by inhibiting NS5A.

Patients should be aware of the most common side effects when using glecaprevir and pibrentasvir tablets, including headache and fatigue, which may affect more than 10% of patients. In addition, glecaprevir and pibrentasvir tablets are not suitable for patients with severely reduced liver function. Therefore, doctors will evaluate the patient's liver function before starting treatment.

在药物使用上，格卡瑞韦哌仑他韦片与某些药物的联合使用是禁止的，以防止潜在的药物相互作用。 For example, cholesterol-lowering drugs such as atorvastatin and simvastatin, dabigatran etexilate (an anticoagulant drug), ethinyl estradiol-containing products (such as birth control pills), rifampicin (an antibiotic commonly used for tuberculosis), carbamazepine, phenytoin, primidone (a drug that treats epilepsy), and St. John's wort (an herbal medicine used to treat depression and anxiety) should not be combined with glecaprevir and pibrentasvir.这些禁忌药物的共同使用可能会导致疗效降低或增加不良反应的风险。

Regarding the side effects and usage restrictions of glecaprevir and pibrentasvir tablets, patients should carefully read the complete list in the package leaflet and consult a doctor for professional guidance and advice.

In short, as an effective hepatitis C treatment drug, glecaprevir and pibrentasvir tablets need to follow relevant contraindications and precautions during use to ensure maximum safety and efficacy.

参考资料：https://www.mavyret.com/