What is the latest market price of one dose of Enactuzumab in 2025?

Eranatamab (Elranatamab) is a new bispecific T-cell engaging antibody targeting BCMA (B cell maturation antigen). It is currently mainly used to treat patients with multiple myeloma (RRMM) who have relapsed or been refractory after multiple lines of treatment. As an important member of immunotherapy, it achieves precise identification and elimination of malignant plasma cells by connecting CD3 on the surface of T cells and BCMA on the surface of tumor cells, thereby improving the immune system's ability to fight tumors. This mechanism allows it to show a high response rate and durability in patients with refractory myeloma, and is especially suitable for patients who are resistant to traditional therapies or have no standard treatment options after relapse.

In the Chinese market, enantuzumab has completed marketing registration and been approved, marking the official entry of this globally innovative drug into the field of hematological tumor treatment in China. At present, it has not been included in the national medical insurance catalog, so patients face high out-of-pocket costs in clinical applications. According to market disclosure information, the main specifications of eractuzumab currently sold in China are in the form of a solution for subcutaneous injection, including 44mg (1.1ml) and 76mg (1.9ml), which are used according to the treatment course design and dose escalation principles. The price of each box is about RMB 40,000, depending on the dosage form and drug purchase channel.

In the overseas market, eractuzumab was developed by Pfizer and has received accelerated approval from the US FDA. The brand name is Elrexfio and is used to treat patients with relapsed and refractory multiple myeloma who have received four or more therapies in the past. The price of original medicines in the United States is more than US$8,000 per box. There are currently no generic versions of eractuzumab officially on the market, which means that only Pfizer’s original version is available on the market. For more information on overseas drug prices and related information, please consult Yaode Medical Consultants.

Reference materials:https://www.drugs.com/mtm/elranatamab.html