What is the trade name for bedaquiline? What are the brands

Bedaquiline (Bedaquiline) is a new anti-tuberculosis drug, mainly used to treat multidrug-resistant pulmonary tuberculosis (MDR-TB). It is the first new drug approved for this indication in the past 50 years. Its mechanism of action is unique. It interferes with bacterial energy metabolism by inhibiting the ATP synthase of Mycobacterium tuberculosis, and has significant bactericidal activity. The drug was first approved by the U.S. Food and Drug Administration (FDA) in 2012 for the treatment of adult patients with multidrug-resistant pulmonary tuberculosis under the trade name Sirturo. Sirturo is currently the most well-known brand name of bedaquiline in the world, representing the standard version of the original drug.

Sirturo, as a key ingredient in anti-tuberculosis treatment programs in many countries around the world, has been included in the list of essential drugs by the World Health Organization (WHO). Its position is particularly important in the treatment of MDR-TB, and it is often used as part of a combination treatment program to improve the success rate of treatment. In addition to the original brand Sirturo, generic versions produced by other pharmaceutical companies are gradually appearing around the world. For example, pharmaceutical companies in India, Laos and other countries have produced quality-assured generic drugs in accordance with the World Health Organization Prequalification Program (WHO Prequalification Program). Although these generic drugs do not use the "Sirturo" trademark, their active ingredients are the same as the original drugs, and the dosage is usually 100mg tablets.

The registered name of bedaquiline may be slightly different in different countries, but its international nonproprietary name (INN)bedaquiline remains consistent. When purchasing the drug, patients should pay attention to distinguishing the brand name from the generic name, and ensure that the drug packaging label, manufacturer, drug batch number and other information are complete to ensure the safety of the drug. Bedaquiline is the core drug for the treatment of drug-resistant tuberculosis. The brand behind it not only reflects the difference in source, but also affects the stability of the efficacy and drug regulatory standards. Therefore, you need to be extra cautious when selecting it.

Reference materials:https://en.wikipedia.org/wiki/Bedaquiline