How much does a bottle of enzalutamide/enzalutamide cost in 2025?

Enzalutamide/Enzalutamide ( Enzalutamide) is a targeted drug used to treat prostate cancer and is an androgen receptor inhibitor. This drug is mainly used to treat castration-resistant prostate cancer, especially if the disease progresses despite other treatments, such as hormone therapy or chemotherapy. Enzalutamide interferes with the androgen signaling pathway through multiple mechanisms, including inhibiting the transport of androgen receptors, preventing its binding to androgens, and interfering with the downstream signaling of the receptors, thereby effectively preventing the growth and spread of tumor cells.

In terms of clinical application, enzalutamide is generally recommended for patients who have been diagnosed with metastatic castration-resistant prostate cancer and is suitable for continued use after multiple treatment options have failed. Studies have shown that enzalutamide can significantly prolong the progression-free survival and overall survival of patients, and its side effects are relatively controllable. Common adverse reactions include fatigue, hypertension, diarrhea, etc., and are usually tolerated.

In China, the original drug of enzalutamide is available in the form of soft capsules and has been included in the reimbursement scope of Class B medical insurance, which has reduced the financial burden of patients to a certain extent. The more common specifications on the general market are 40mg*112 capsules, and the market price per box is about 6,000 yuan.

In comparison, the price of enzalutamide in overseas markets is generally higher. For example, in Türkiye, the price of original drugs of the same specifications may exceed 10,000 yuan, and due to exchange rate fluctuations, the actual cost may be higher. In addition, many countries and regions also provide generic drugs of enzalutamide. For example, the generic drugs produced in India are priced at more than 2,000 yuan, making them the choice of some patients. Generic drugs are similar in ingredients to original drugs, but due to production costs, market strategies and other reasons, the prices are relatively more competitive.

Reference materials:https://www.xtandi.com/