The price of adagrasib is revealed: a comparative analysis of original drugs and generic drugs

Adagrasib is a new type of small molecule targeted drug, mainly used to treat non-small cell lung cancer (NSCLC) carrying KRAS G12C mutation. KRAS gene mutations play an important role in various cancers, and G12C mutation is a specific and common type. Adagrasib effectively prevents the growth and metastasis of cancer cells by inhibiting the activity of this mutant KRAS protein. The drug received accelerated approval from the FDA in 2022, providing a new treatment option for patients who have failed to respond to other treatments.

Regarding the price of adagrasib, it has not yet been officially launched in China, so patients usually need to purchase it through foreign channels. The specification of the original drug is 200mg*180 tablets, and the market price is as high as hundreds of thousands of yuan, which is indeed a huge financial burden for most patients. This high price puts many patients under greater financial pressure when receiving treatment.

In contrast, there are also some generic versions on the market, particularly versions from Laos. Its specification is 200mg*90 tablets, and the price per box is about more than 3,000 yuan, which is significantly lower than the price of the original drug. This makes it financially easier for some patients to obtain the treatment they need. However, although the price of generic drugs is more affordable, patients still need to be cautious when choosing, ensuring that the source of the drugs they purchase is regular and that the ingredients are basically the same as the original drugs to ensure safety and efficacy.

In general, adagrasib, as a targeted treatment drug focusing onKRAS G12C mutation, brings new hope to lung cancer patients. Although original drugs are expensive, the emergence of generic drugs provides patients with more choices. When purchasing, patients should carefully weigh the cost of the drug against the potential therapeutic effect, and conduct treatment under the guidance of a doctor to ensure that the economic burden is minimized while ensuring the therapeutic effect.

References：https://www.krazati.com/