How much does a box of inclisiran cost in 2025, the latest selling price and purchase channels

Inclisiran sodium (inclisiran) is an innovative drug used to lower low-density lipoprotein cholesterol (LDL-C). It is mainly suitable for patients with familial heterozygous hypercholesterolemia (HeFH) and patients with clinical atherosclerotic cardiovascular disease (ASCVD) risk. It is administered by subcutaneous injection, usually with a second injection 3 months after the initial injection and every 6 months thereafter. This dosing mode not only improves treatment compliance, but also provides patients with a relatively convenient medication experience.

Currently, the original drug Inkslan Sodium has been launched in China, but due to its short time on the market, it has not yet been included in the scope of medical insurance reimbursement, so patients need to purchase it at their own expense. In the domestic market, the specifications of Inkslan sodium are generally 284mg/1.5ml, and the price per box is about RMB 10,000. Considering the frequency of drug use, this undoubtedly places a financial burden on patients.

In comparison, the original drug Inkslan sodium sold in overseas markets has a specification of 284mg/1.5ml*2 bottles, and the price per box may be as high as more than 40,000 yuan (The price may fluctuate due to the exchange rate). It is worth noting that, whether in the domestic or international market, there are currently no generic drugs of Inkslan sodium on the market, which means that patients face relatively limited choices when choosing treatment options.

In terms of purchasing channels, patients can purchase through the hospital pharmacy or designated drug retailers, usually with a prescription issued by a doctor. Due to the special characteristics of Inkslan sodium, it may sometimes be necessary to purchase and inject it in a specialized medical institution or clinic to ensure that the storage and use of the drug comply with regulations. In addition, some hospitals may form partnerships with drug suppliers to provide patients with easier access.

Reference materials:https://www.drugs.com/price-guide/leqvio