How much does Teriflunomide cost?

Teriflunomide, sold under the trade nameAubagio, is the main active in vivo metabolite of leflunomide. After leflunomide administration, 70% of the administered drug is converted to teriflunomide. Teriflunomide is a drug containing the active substanceteriflunomide, which is used to treat people over 10 years old with multiple sclerosis (MS), a disease in which inflammation destroys the protective sheath around nerves.

Teriflunomide is used in a type of MS called relapsing-remitting multiple sclerosis, in which patients experience a flare-up of symptoms (relapse) followed by periods of recovery (remission). Teriflunomide is currently only available through a doctor's prescribing information, and treatment with the drug needs to be under the guidance and supervision of a doctor. Teriflunomide has been found to block the transcription factorNF-κB. It also inhibits tyrosine kinases, but only at high doses and is not used clinically. It is uncertain whether this explains its effect on multiple sclerosis lesions (MS).

Teriflunomide The original drug has been launched in China and has entered the scope of medical insurance through medical insurance reimbursement standards. It may be limited to multiple sclerosis patients who are ineffective in conventional treatments. However, the reimbursement ratio is different in different regions, and the price after reimbursement is different. The price of 14mg*28 tablets per box is around 10,000 yuan, which is expensive. Cheaper generic drugs are also sold in other overseas countries. The pharmaceutical ingredients of generic drugs are basically the same as those of the original drugs. The price of each box of 14mg*30 tablets produced by an Indian pharmaceutical factory is around RMB 800 (the price may fluctuate due to exchange rates).