Tolvaptan side effects

Tolvaptan is a drug used to treat low sodium levels in the blood. It is sold under the trade names Samsca and Jynarque. Tolvaptan is used to treat abnormally low sodium levels in the blood of adults, a condition called syndrome of inappropriate antidiuretic hormone secretion (SIADH). In SIADH, an excess of the hormone vasopressin causes patients to produce less urine and thus retain more water in the body, which dilutes the concentration of sodium in the blood.

May affect more than1/10 patients. The most common side effects of tolvaptan tablets are thirst, nausea and rapid rise in sodium levels. Tolvaptan Tablets should not be used in patients who are anuria (inability to urinate), very low blood volume, hypovolemia and low blood sodium levels, hypernatremia (abnormally high levels of sodium in the blood), or patients who cannot feel thirst. It should not be used in patients who are allergic to tolvaptan or medicines similar to tolvaptan (so-called benzazepines or their derivatives). Tolvaptan tablets should also not be used by pregnant or breastfeeding women.

Tolvaptan tablets have been marketed in China and have entered the scope of Class B medical insurance. The price paid by medical insurance is relatively cheap, but the reimbursement ratio is different in different regions, and the price after reimbursement will be different. Domestic pharmacies or hospitals will sell this drug, and the original drug of tolvaptan tablets is also on the market overseas. There are also generic tolvaptan tablets produced in other countries. The price of Indian pharmaceutical factory production specifications15mg*4 tablets per box is around RMB 800 (the price may fluctuate due to the exchange rate). The ingredients of foreign generic drugs are basically the same as those of domestic and foreign original drugs.