Contraindications while taking baricitinib

Baricitinib (Baricitinib) may be contraindicated in certain circumstances, that is, there are contraindications to its use. The following are some common contraindications to baricitinib:

1.Allergic reaction: If the patient has an allergic reaction to baricitinib or similar drugs, such as urticaria, difficulty breathing, throat swelling, etc., then baricitinib is contraindicated.

2.Active serious infection: Baricitinib suppresses the immune system and increases the risk of infection. Therefore, the use of baricitinib is contraindicated in patients with active severe infection.

3.Tuberculosis: Use of baricitinib may increase the risk of recurrence of tuberculosis. Therefore, the use of baricitinib is contraindicated in patients with active tuberculosis or a history of exposure to tuberculosis.

4.Deep fungal infection: The use of baricitinib may lead to an increased risk of deep fungal infection. Therefore, baricitinib is contraindicated in patients with deep fungal infections.

5.Major cardiovascular events: The use of baricitinib may be associated with an increased risk of cardiovascular events (eg, myocardial infarction, stroke). The use of baricitinib is contraindicated in patients who have experienced a major cardiovascular event.

6.Severe hepatic impairment: The use of baricitinib is contraindicated in patients with severe hepatic impairment.

In addition to the above contraindications, baricitinib also has some potential risks and side effects. Therefore, before deciding to use baricitinib, physicians should conduct a thorough patient evaluation and weigh the potential benefits and risks. Specific individual circumstances may require special attention or additional monitoring measures to ensure the safety and effectiveness of the drug. Baricitinib or any other medicine should be used only under the guidance of a physician and based on the specific circumstances of the individual patient.