How to take Trametinib

Trametinib (Trametinib) should be used according to the doctor's advice and prescription, adhere to the accurate dosage, frequency and duration, and do not change the medication method at will. Trametinib is generally available as an oral tablet. When taking the medicine, swallow the tablet whole with an appropriate amount of water. Do not chew, break or grind the tablet. The recommended dose of trametinib is 2 mg once daily, which should be taken on an empty stomach at least 1 hour before or 2 hours after a meal. It usually needs to be taken at the same time every day to ensure stable blood concentration of the drug. Try to avoid missing doses of Trametinib, as good medication compliance is crucial to the effectiveness of the drug. Take the missed dose as soon as you remember. However, if your next scheduled dose is less than 12 hours away, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose.

The original drug of trametinib has been launched in China and has entered the scope of Class B medical insurance, but it may only be purchased by patients who meet the indications of trametinib, such as BRAF V600 mutation-positive unresectable or metastatic melanoma. Its price is around 10,000 to 20,000 yuan. The reimbursement ratio is different in different regions, and the price is also different, making it expensive. The price of the Turkish version of the original drug Trametinib listed overseas is around RMB 7,900 (the price may fluctuate due to the exchange rate). The price of the generic version of Trametinib produced by the Lao pharmaceutical factory is around RMB 2,950 (the price may fluctuate due to the exchange rate). The ingredients and efficacy of foreign generic drugs are basically the same as those of the domestic and foreign original drugs.