Is Trametinib included in medical insurance? How much does it cost?

Trametinib (Trametinib)The original drug has been marketed in China and has entered the scope of Class B medical insurance. It may only be purchased by patients who meet the indications of trametinib, such as combined with dabrafenib mesylate for treatmentBRAF Patients with V600 mutation-positive unresectable or metastatic melanoma and their adjuvant treatment after complete resection, combined with dabrafenib mesylate, are suitable for the treatment of patients with BRAF V600 mutation-positive metastatic non-small cell lung cancer. The price of 2mg*30 tablets is around RMB 10,000-20,000. The reimbursement ratio is different in different regions, and the price is also different, making it expensive.

Trametinib has shown relatively good efficacy in the treatment of BRAF V600 mutation-positive malignant melanoma and non-small cell lung cancer, and can significantly extend progression-free survival and overall survival. In multiple clinical trials, patients who received trametinib in combination with other drugs showed better survival rates than those who received chemotherapy or other targeted drugs alone. In one study, some patients' tumors were observed to shrink significantly or stop growing after treatment with trametinib.

Specifications of the Turkish version of Trametinib original drug marketed overseasThe price of 2mg*30 tablets per box is around 7,900 RMB (the price may fluctuate due to exchange rates), and is also produced in other countries. The price of a box of 2mg*30 tablets produced by a Lao pharmaceutical factory for trametinib generics is around RMB 2,950 (the price may fluctuate due to exchange rates). The ingredients and efficacy of foreign generics are basically the same as those of domestic and foreign original drugs.