The difference between imported and domestically produced Tofacitinib

Tofacitinib (Tofacitinib) The ingredients and efficacy of imported drugs and domestic drugs are basically the same, but the manufacturers, specifications and prices are different. Tofacitinibis a drug that belongs to the Janus kinase (JAK) inhibitor class. It is mainly used to treat certain autoimmune diseases, especially rheumatoid arthritis (RA). Tofacitinib's therapeutic effects stem from its ability to inhibit a specific enzyme called JAK, which plays a role in signaling pathways in the immune system. By blocking JAK, tofacitinib helps regulate immune responses and reduce inflammation associated with autoimmune diseases.

Tofacitinib is used to treat certain types of arthritis(such as psoriatic arthritis, rheumatoid arthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis pcJIA) and helps reduce joint pain/tenderness/swelling. Tofacitinib is also used to treat a certain intestinal disorder (ulcerative colitis) and can help reduce the symptoms of ulcerative colitis, such as diarrhea, rectal bleeding, and stomach pain.

Tofacitinib has been launched in China and has entered the scope of Class B medical insurance. The common specification is tofacitinib citrate tablets. The price paid by medical insurance is relatively cheap, butthe reimbursement ratio is different in different regions, and the price after reimbursement will be different. Overseas, there are also generic drugs of tofacitinib produced in other countries. The price of each box produced by a Bangladeshi pharmaceutical factory is around 300 yuan (the price may fluctuate due to the exchange rate). The ingredients of domestic original drugs and foreign generic drugs are basically the same, and the prices of different specifications will be different.