What conditions can Tofacitinib treat?

Tofacitinib (Tofacitinib)Contains the active ingredientTofacitinib is a Janus kinase (JAK) inhibitor drug that works by reducing the activity of the immune system and preventing the body's response to cytokine signals. Tofacitinib is used to treat rheumatoid arthritis alone or with other drugs in adults who cannot take or have not responded to one or more tumor necrosis factor (TNF) inhibitor drugs.

Tofacitinib is also used to treat psoriatic arthritis and ulcerative colitis in adults who are unable to take or who have not responded to or tolerated one or more TNF inhibitor drugs. It is also used to treat polyarticular juvenile idiopathic arthritis, which affects five or more joints in the first six months of the condition, causing pain, swelling and loss of function, in children 2 years and older who cannot take it or who have not responded to one or more TNF inhibitor drugs.

Tofacitinibhas been launched in China and has entered the scope of Class B medical insurance. The common specification is tofacitinib citrate tablets. The price paid by medical insurance is relatively cheap, but the reimbursement ratio is different in different regions, and the price after reimbursement will be different. Overseas, there are also tofacitinib generic drugs produced in other countries. The price of each box produced by a Bangladeshi pharmaceutical factory is around RMB 300 (the price may fluctuate due to the exchange rate). The ingredients of domestic original drugs and foreign generic drugs are basically the same, and the prices of different specifications will be different.