Analysis of the main functions, side effects and clinical use precautions of EIKANCE 0.01% atropine sulfate eye drops

0.01% atropine sulfate eye drops (EIKANCE) is a low-concentration atropine ophthalmic preparation, mainly used to delay the progression of myopia in children. Atropine is an anticholinergic drug that antagonizes the parasympathetic nerve effects of the ciliary muscles in the eye and reduces accommodative tension, thus inhibiting the excessive growth of the axial length of the eye. Low-concentration atropine eye drops retain the efficacy while significantly reducing side effects. Compared with traditional high-concentration atropine, they are more suitable for long-term use, and are especially widely used in the prevention and control of myopia in children and adolescents.

Clinical studies have shown that 0.01%Atropine Sulfate Eye Drops can effectively slow down the progression of myopia. Multiple randomized controlled trials have shown that it can delay the growth of the axial length by about 0.1–0.2 millimeters per year, which is equivalent to reducing the progression rate of myopia by about 30–50%. This effect is particularly obvious after 1–2 years of continuous use. For high-risk children, such as those with familial myopia or early-onset myopia, long-term use can significantly reduce the probability of high myopia. Eye drops are usually administered once daily and are recommended for use at night to reduce the effects of light sensitivity or blurred vision.

Although0.01%atropine eye drops has a low concentration, certain side effects may still occur. The most common include mild light sensitivity, accommodation difficulties due to transient cycloplegia, and occasional dry eyes or burning sensation in the eyes. Some children may have slight mydriasis, resulting in a slight decrease in near vision, but most do not require special intervention and can be improved by wearing moderate myopia auxiliary lenses. Rarely, local allergic reactions such as eyelid redness or conjunctival congestion may occur. With long-term use, ophthalmologists usually recommend regular follow-up visits to monitor axial length and corneal health.

In terms of precautions for use, parents should strictly follow the doctor's instructions and should not increase the dosage or frequency at will to avoid increasing the risk of adverse reactions. Wash your hands before dropping the medicine to prevent eye infection; children can close their eyes for one minute after dropping the medicine to promote absorption of the medicine, but avoid rubbing their eyes. Children with a history of glaucoma, keratitis, or serious eye infections should be used with caution under the guidance of a physician. The medicinal solution needs to be stored away from light to avoid high temperatures or accidental ingestion by children. If you experience persistent eye pain, significant loss of vision, or severe allergic reaction during use, you should stop taking the medicine immediately and seek medical advice.

In clinical practice, 0.01%Atropine Sulfate Eye DropsEIKANCE is not only used to prevent and control myopia alone, but can also be used in combination with optical correction methods such as orthokeratology lenses or progressive multifocal glasses to obtain better myopia control effects. The study found that the combined program was more effective among high-risk children, and could further delay axial growth and reduce the incidence of high myopia and related complications.

In terms of medication management, parents should take their children to professional ophthalmologists for regular follow-up visits, including visual acuity examination, axial length measurement and corneal health assessment. For children with poor medication compliance, doctors can help parents standardize the medication drip time through reminder tools or recording forms. During long-term use, pay attention to monitor changes in light sensitivity and near vision, and adjust the lighting environment appropriately or use auxiliary glasses if necessary.

In general, 0.01%Atropine Sulfate Eye Drops (EIKANCE) has become an important drug for the prevention and control of myopia in children and adolescents due to its low concentration, high safety and long-term use. Rational use can significantly slow down the growth of the axial length of the eye and reduce the risk of high myopia, but individual differences and potential side effects still need to be paid attention to. Through doctor's guidance, standardized medication dripping and regular follow-up, the efficacy of the medication can be maximized while ensuring medication safety and providing scientific protection for children's vision health.

Keyword tags: Atropine sulfate eye drops, children's myopia, axial control, long-term use, safety

Reference materials:https://medlineplus.gov/druginfo/meds/a601018.html