Explanation of overseas purchase channels and price of pacritinib

Pacritinib is an oral tyrosine kinase inhibitor mainly used to treat patients with primary myelofibrosis or other high-risk myeloproliferative diseases, especially those with low platelet counts. The drug slows down the progression of myelofibrosis and improves hematological indicators by inhibiting signaling pathways such as JAK2 and FLT3. Clinically, pacitinib usually needs to be used under the guidance of a hematologist, and the dosage and course of treatment should be adjusted according to the patient's condition.

In foreign markets, the original drug of pacitinib is mainly sold in the United States. The US version of the original medicine is relatively expensive, with a box of medicine usually selling for more than 200,000 yuan. Due to the high price of original drugs, they are usually available to patients with financial conditions or through international medical channels. A formal prescription must be provided when purchasing, and the transaction must be completed at a compliant pharmacy or hospital to ensure drug quality and legality.

In addition to the original drug, the overseas market also has the supply of generic pacitinib produced by Lucius Pharmaceuticals of Laos. The price of this generic version is relatively low, with each box selling for about more than 10,000 yuan, and the drug ingredients are basically the same as the original drug. The emergence of generic drugs has provided patients with a more economical choice, but they still need to purchase through formal channels to ensure that the source of the drug is reliable and used under the guidance of a doctor to avoid problems with dosage and efficacy.

For patients who intend to purchase pacitinib across borders, they need to pay attention to the legality of the purchase channel, drug transportation conditions, and customs clearance regulations. It is recommended to give priority to regular overseas pharmacies or medical institutions and ensure that prescriptions and usage plans comply with local laws and regulations. At the same time, patients should evaluate their own financial situation and clinical needs before purchasing drugs, and formulate a reasonable medication plan based on doctor's recommendations to ensure the safety and effectiveness of treatment.

Keyword tags: pacitinib, myelofibrosis, overseas drug purchase, Laos generic drugs, price

Reference materials:https://pubmed.ncbi.nlm.nih.gov/35567653/