The best daily taking time and precautions for crizotinib (Xalkori)

It is usually recommended to take Crizotinib (Crizotinib) orally at a fixed time every day as prescribed by the doctor to ensure stable blood concentration and enhance drug efficacy. It is generally recommended to take it at the same time every day. You can choose to take it in the morning or evening according to your personal schedule. However, you should try to avoid frequently changing the taking time. Regular medication can reduce blood drug concentration fluctuations, reduce the risk of drug resistance, and help patients form good medication habits.

When taking the medicine, swallow the tablet whole and do not chew or crush it to avoid affecting drug absorption and bioavailability. Crizotinib can be taken before or after a meal, but it is recommended to swallow it with water. It is not recommended to take it with a high-fat meal to avoid affecting drug absorption. If vomiting occurs, you should follow your doctor's advice to decide whether to take another dose, and do not repeat the dose on your own.

While taking crizotinib, it is necessary to monitor heart and liver function. This drug may cause prolongation of the ECGQT interval, liver function abnormalities, or visual disturbances, so doctors usually recommend hematology tests, liver function evaluation, and ECG monitoring before starting the drug and during treatment. Patients should inform their doctor promptly if they experience palpitations, blurred vision, or unusual fatigue.

In addition, patients should avoid concurrent use of drugs that may affect drug metabolism while taking crizotinib, including certain antifungals, antibiotics, and antiepileptic drugs. Drinking and smoking should be avoided as much as possible in life to reduce the burden on the liver. Complying with these precautions will help improve drug efficacy, reduce the incidence of adverse reactions, and ensure the safety and continuity of treatment.

Reference materials:https://www.drugs.com/